Estrogen receptor signaling mechanisms

N Fuentes, P Silveyra - Advances in protein chemistry and structural …, 2019 - Elsevier
The primary female sex hormones, estrogens, are responsible for the control of functions of
the female reproductive system, as well as the development of secondary sexual …

Anti-inflammatory actions of glucocorticoids: molecular mechanisms

PJ Barnes - Clinical science, 1998 - portlandpress.com
1. Glucocorticoids are widely used for the suppression of inflammation in chronic
inflammatory diseases such as asthma, rheumatoid arthritis, inflammatory bowel disease …

Steroid receptor interactions with heat shock protein and immunophilin chaperones

WB Pratt, DO Toft - Endocrine reviews, 1997 - academic.oup.com
I. Introduction II. 9S Receptors A. Estrogen receptors (ERs) B. Progesterone receptors (PRs)
C. Androgen receptors (ARs) D. Glucocorticoid receptors (GRs) E. Mineralocorticoid …

Androgen receptor defects: historical, clinical, and molecular perspectives

CA Quigley, A De Bellis, KB Marschke… - Endocrine …, 1995 - academic.oup.com
I. Introduction IN 1953 lohn Morris, an obstetrician at Yale University, reported a series of 82
individuals (80 cases collated from the literature and two cases of his own) who had a …

Role of transcriptional activation of IκBα in mediation of immunosuppression by glucocorticoids

RI Scheinman, PC Cogswell, AK Lofquist… - Science, 1995 - science.org
Glucocorticoids are potent immunosuppressive drugs, but their mechanism is poorly
understood. Nuclear factor kappa B (NF-κB), a regulator of immune system and inflammation …

Endoplasmic reticulum stress and homeostasis in reproductive physiology and pathology

E Guzel, S Arlier, O Guzeloglu-Kayisli… - International journal of …, 2017 - mdpi.com
The endoplasmic reticulum (ER), comprises 60% of the total cell membrane and interacts
directly or indirectly with several cell organelles ie, Golgi bodies, mitochondria and …

Steroid hormone receptors: many actors in search of a plot

M Beato, P Herrlich, G Schütz - Cell, 1995 - Elsevier
It tookalmost aquarterof acenturyfrom the earliest indication that steroid hormones play a
role in transcriptional control, triggered by the observation by Ulrich Clever of …

Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids

CM Bamberger, HM Schulte, GP Chrousos - Endocrine reviews, 1996 - academic.oup.com
I. Introduction S TEROID hormones are essential constituents of the intercellular
communication system that maintains homeostasis in higher organisms. Glucocorticoids, a …

Diagnosis and treatment of depression in late life: consensus statement update

BD Lebowitz, JL Pearson, LS Schneider, CF Reynolds… - Jama, 1997 - jamanetwork.com
Objective.—To reexamine the conclusions of the 1991 National Institutes of Health
Consensus Panel on Diagnosis and Treatment of Depression in Late Life in light of current …

Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1β-induced histone H4 acetylation on lysines 8 and 12

K Ito, PJ Barnes, IM Adcock - Molecular and cellular biology, 2000 - Am Soc Microbiol
We have investigated the ability of dexamethasone to regulate interleukin-1β (IL-1β)-
induced gene expression, histone acetyltransferase (HAT) and histone deacetylase (HDAC) …