Non-transfusion-dependent thalassemia: a panoramic review

H Shash - Medicina, 2022 - mdpi.com
Non-transfusion-dependent thalassemia (NTDT) has been considered less severe than its
transfusion-dependent variants. The most common forms of NTDT include β-thalassemia …

Recent progress in gene therapy and other targeted therapeutic approaches for beta thalassemia

EM Hamed, MH Meabed, UF Aly… - Current Drug …, 2019 - ingentaconnect.com
Beta-thalassemia is a genetic disorder characterized by the impaired synthesis of the
betaglobin chain of adult hemoglobin. The disorder has a complex pathophysiology that …

Efficacy of oral acetaminophen and intravenous chlorpheniramine maleate versus placebo to prevent red cell transfusion reactions in children and adolescent with …

P Rujkijyanont, C Monsereenusorn, P Manoonphol… - Anemia, 2018 - Wiley Online Library
Background. Thalassemia is a common congenital hemolytic disorder. In severe cases,
regular blood transfusion is essentially required. The role of premedications to prevent …

Subclinical left ventricular dysfunction in children and adolescence with thalassemia intermedia

R Isa Tafreshi, M Radgoodarzi… - Frontiers in …, 2022 - frontiersin.org
Background Cardiac complications are important causes of morbidity in patients with
thalassemia intermedia (TI). We aimed to assess left ventricular (LV) function, using new …

Molecular characterization of β-thalassemia intermedia in the West Bank, Palestine

R Faraon, M Daraghmah, F Samarah, MA Srour - BMC hematology, 2019 - Springer
Background We aimed to investigate the molecular basis of β-Thalassemia intermedia (TI) in
the West Bank region and its management practices. Methods This was a case series multi …

Erythroferrone level in β-thalassemia patients

H Saad, SM Bahgat, DM El Dewy… - Journal of Recent …, 2021 - jram.journals.ekb.eg
Background: β thalassemia patients have repeated blood transfusions those lead to iron
overload, resulting in iron toxicity. In such cases Hepcidin results in excessive iron …

Beta-Talasemia: Un mundo de complicaciones con nuevas alternativas de tratamiento.

MC Alzate - Archivos de Medicina (Manizales), 2019 - revistasum.umanizales.edu.co
Introducción: β-talasemia, es causada por mutaciones en el gen de la globina HBB, que
codifica la subunidad β de la HbA. La enfermedad es conocida por ser altamente prevalente …

[PDF][PDF] Serum hepcidin and ferritin level changes in iraqi adult patients with non-transfusion dependent beta-thalassemia major and intermedia

EA Ali, A Albayati, SA Alshaban, K Ali - Int J Pharm Res, 2021 - researchgate.net
Background and objectives: Non-transfusion dependent thalassemia (NTDT) characterized
by an increase iron overload with end-organ damage as a consequence. The aim of the …

[PDF][PDF] Extramedullary hematopoiesis in the facial sinus in a patient homozygous for Hemoglobin Lepore: the first case in literature

V Talarico, L Muraca, PP Arcuri… - Eur Rev Med …, 2021 - europeanreview.org
Extramedullary hematopoiesis (EMH) is a proliferation of hematopoietic tissue outside the
bone marrow. The most affected areas are paravertebral ones. We report the case of a …

Gene Therapy: A Revolutionary Step in Treating Thalassemia

RA Attia, GSA Qureshi, M Safdar, A Raafat… - 2024 - preprints.org
Beta thalassemia is an inherited blood disorder that results in inefficient erythropoiesis due
to genetic mutation that leads to reduction or absence of the hemoglobin beta-globulin …