Background: Despite a reduction in the global burden of malaria, the disease remains
responsible for 214 million cases and 438,000 deaths annually with 88% of the mortality …

Haemoglobin degradation during the erythrocytic life stages is the major function of the food
vacuole (FV) of Plasmodium falciparum and the target of several anti-malarial drugs that …

Background Transcriptional responses to small molecules can provide insights into drug
mode of action (MOA). The capacity of the human malaria parasite, Plasmodium falciparum …

A high performance liquid chromatography method for the determination of fenofibric acid
(FA), the active form of fenofibrate (FBT) in human plasma was developed and validated with …

A sensitive, high-throughput and economic liquid chromatographic method for determination
of fenofibric acid in human plasma was developed and validated by ultraviolet detection and …

Молекулы биологически активных веществ проникают через клеточные мембраны не
только пассивной диффузией, но и с помощью транспортных систем, связанных с …

Malaria, an infectious disease begins with the introduction of protists into blood circulation
and may cause death in severe cases. Development of resistance in Plasmodium parasites …

Topicality. Metabolic syndrome (MS) is an extremely common medical and social problem.
However, there is no modern understanding of the MS ethiopathogenetic mechanisms …

The interest in Nature as a source of potential chemotherapeutic agents continues. Natural
products and their derivatives represent more than 50% of all the drugs in clinical use in the …

Malaria remains the leading cause of death in children under the age of 5 years in sub-
Saharan Africa. While massive efforts to control the disease have recently been launched …