Chemotherapy side-effects: not all DNA damage is equal
WMC van den Boogaard, DSJ Komninos, WP Vermeij - Cancers, 2022 - mdpi.com
Simple Summary The number of children and adults with cancer that are completely cured is
still increasing thanks to effective anti-cancer therapy, but they may be confronted with the …
still increasing thanks to effective anti-cancer therapy, but they may be confronted with the …
Recent advances in models, mechanisms, biomarkers, and interventions in cisplatin-induced acute kidney injury
SJ Holditch, CN Brown, AM Lombardi… - International journal of …, 2019 - mdpi.com
Cisplatin is a widely used chemotherapeutic agent used to treat solid tumours, such as
ovarian, head and neck, and testicular germ cell. A known complication of cisplatin …
ovarian, head and neck, and testicular germ cell. A known complication of cisplatin …
Use of intravenous iodinated contrast media in patients with kidney disease: consensus statements from the American College of Radiology and the National Kidney …
MS Davenport, MA Perazella, J Yee, JR Dillman… - Radiology, 2020 - pubs.rsna.org
Intravenous iodinated contrast media are commonly used with CT to evaluate disease and
to determine treatment response. The risk of acute kidney injury (AKI) developing in patients …
to determine treatment response. The risk of acute kidney injury (AKI) developing in patients …
[HTML][HTML] Drug-induced nephrotoxicity
GTM Sales, RD Foresto - Revista da Associação Médica Brasileira, 2020 - SciELO Brasil
Acute kidney injury is a very common diagnosis, present in up to 60% of critical patients, and
its third main cause is drug toxicity. Nephrotoxicity can be defined as any renal injury caused …
its third main cause is drug toxicity. Nephrotoxicity can be defined as any renal injury caused …
Acute kidney injury
Acute kidney injury (AKI) is defined by a rapid increase in serum creatinine, decrease in
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …
The link between kidney disease and cancer: complications and treatment
J Malyszko, P Tesarova, G Capasso, A Capasso - The Lancet, 2020 - thelancet.com
Acute and chronic kidney disease encompasses a complex set of diseases that can both
lead to, and result from, cancer. In particular, kidney disease can arise from the use of …
lead to, and result from, cancer. In particular, kidney disease can arise from the use of …
Adjuvant role of Salvia miltiorrhiza bunge in cancer chemotherapy: A review of its bioactive components, health-promotion effect and mechanisms
J Huang, J Zhang, C Sun, R Yang, M Sheng… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Chemotherapy is a common cancer treatment strategy.
However, its effectiveness is constrained by toxicity and adverse effects. The Lamiaceae …
However, its effectiveness is constrained by toxicity and adverse effects. The Lamiaceae …
Kidney-based in vitro models for drug-induced toxicity testing
The kidney is frequently involved in adverse effects caused by exposure to foreign
compounds, including drugs. An early prediction of those effects is crucial for allowing novel …
compounds, including drugs. An early prediction of those effects is crucial for allowing novel …
[HTML][HTML] Nephrotoxicity in cancer treatment: An overview
MLC Santos, BB de Brito, FAF da Silva… - World journal of …, 2020 - ncbi.nlm.nih.gov
Anticancer drug nephrotoxicity is an important and increasing adverse drug event that limits
the efficacy of cancer treatment. The kidney is an important elimination pathway for many …
the efficacy of cancer treatment. The kidney is an important elimination pathway for many …
[HTML][HTML] Management of hepatotoxicity of chemotherapy and targeted agents
TW Mudd, AK Guddati - American journal of cancer research, 2021 - ncbi.nlm.nih.gov
Hepatotoxicity of chemotherapeutic agents such as methotrexate, oxaliplatin, and irinotecan
have been well documented and characterized allowing for careful management by …
have been well documented and characterized allowing for careful management by …