The human body harbors a diverse ecosystem of microorganisms, including bacteria,
viruses, and fungi, collectively known as the microbiota. Current research is increasingly …

The aetiologies and origins of neurodegenerative diseases, such as Alzheimer's disease
(AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and Huntington's …

Globally, neurodegeneration and cerebrovascular disease are common and growing
causes of morbidity and mortality. Pathophysiology of this group of diseases encompasses …

A diverse and stable microbiota promotes a healthy state, nevertheless, an imbalance in gut
or oral bacterial composition, called dysbiosis, can cause gastrointestinal disorders …

Alzheimer's disease is widely regarded as poorly treated due to poor conceptualization. For
40 years, Alzheimer's disease pathophysiology has focused on two culprits, amyloid-β …

The ageing of an organism is associated with certain features of functional decline that can
be assessed at the cellular level (eg, reduced telomere length, loss of proteostasis, etc.), but …

The origins of Alzheimer's disease (AD) and Parkinson's disease (PD) involve genetic
mutations, epigenetic changes, neurotoxin exposure and gut microbiota dysregulation. The …

Tauopathies constitute a group of neurodegenerative diseases characterized by abnormal
aggregation of the protein tau, progressive neuronal and synaptic loss, and eventual …

Trillions of intestinal bacteria in the human body undergo dynamic transformations in
response to physiological and pathological changes. Alterations in their composition and …

Gut bacteria regulate brain pathology of Alzheimer's disease (AD) patients and animal
models; however, the underlying mechanism remains unclear. In this study, 3-month-old …