Inflammation in intracerebral hemorrhage: from mechanisms to clinical translation

Y Zhou, Y Wang, J Wang, RA Stetler, QW Yang - Progress in neurobiology, 2014 - Elsevier
Intracerebral hemorrhage (ICH) accounts for 10–15% of all strokes and is associated with
high mortality and morbidity. Currently, no effective medical treatment is available to improve …

Mechanism and therapy of brain edema after intracerebral hemorrhage

H Zheng, C Chen, J Zhang, Z Hu - Cerebrovascular diseases, 2016 - karger.com
Background: Intracerebral hemorrhage (ICH) is a subtype of stroke with a severe high
mortality and disability rate and accounts for about 10-15% of all strokes. The oppression …

Interactions within stroke systems of care: a policy statement from the American Heart Association/American Stroke Association

R Higashida, MJ Alberts, DN Alexander, TJ Crocco… - Stroke, 2013 - Am Heart Assoc
Below are outlined some of the key concepts and components of a modern stroke system of
care in the United States. These elements will vary in different parts of the country (and the …

[HTML][HTML] Toll-like receptor 4 signaling in intracerebral hemorrhage-induced inflammation and injury

H Fang, PF Wang, Y Zhou, YC Wang… - Journal of …, 2013 - Springer
Intracerebral hemorrhage (ICH) is a common type of fatal stroke, accounting for about 15%
to 20% of all strokes. Hemorrhagic strokes are associated with high mortality and morbidity …

Toll‐like receptor 2/4 heterodimer mediates inflammatory injury in intracerebral hemorrhage

YC Wang, Y Zhou, H Fang, S Lin, PF Wang… - Annals of …, 2014 - Wiley Online Library
Objective Inflammatory injury plays a critical role in intracerebral hemorrhage (ICH)‐induced
secondary brain injury. However, the upstream events that initiate inflammatory responses …

[HTML][HTML] Clinical review: Canadian national advisory committee on blood and blood products-massive transfusion consensus conference 2011: report of the panel

WH Dzik, MA Blajchman, D Fergusson, M Hameed… - Critical Care, 2011 - Springer
Abstract In June 2011 the Canadian National Advisory Committee on Blood and Blood
Products sponsored an international consensus conference on transfusion and trauma. A …

[HTML][HTML] Intracerebral hemorrhage

D Rajashekar, JW Liang - 2020 - europepmc.org
Intracerebral Hemorrhage - Abstract - Europe PMC Sign in | Create an account https://orcid.org
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Therapeutic potential of puerarin against cerebral diseases: From bench to bedside

T Liu, K Su, W Cai, H Ao, M Li - European Journal of Pharmacology, 2023 - Elsevier
The incidence of cerebral diseases is rapidly increasing worldwide, and they have become
an important challenge for modern medicine. Most of the available chemical drugs used in …

Peroxiredoxin 1-mediated activation of TLR4/NF-κB pathway contributes to neuroinflammatory injury in intracerebral hemorrhage

DL Liu, LX Zhao, S Zhang, JR Du - International Immunopharmacology, 2016 - Elsevier
The proinflammatory properties of extracellular peroxiredoxins (Prxs) via induction of Toll-
like receptor 4 (TLR4) activation have been gradually revealed under diverse stress …

NLRP3 is required for complement-mediated caspase-1 and IL-1beta activation in ICH

ST Yao, F Cao, JL Chen, W Chen, RM Fan, G Li… - Journal of Molecular …, 2017 - Springer
Complement-mediated inflammation plays a vital role in intracerebral hemorrhage (ICH),
implicating pro-inflammatory factor interleukin-1beta (IL-1β) secretion. Brain samples and …