Protein Kinase CK2: A Targetable BCR‐ABL Partner in Philadelphia Positive Leukemias
BCR‐ABL‐mediated leukemias, either Chronic Myeloid Leukemia (CML) or Philadelphia
positive Acute Lymphoblastic Leukemia (ALL), are the paradigm of targeted molecular …
positive Acute Lymphoblastic Leukemia (ALL), are the paradigm of targeted molecular …
[HTML][HTML] Significance and implications of FHIT gene expression and promoter hypermethylation in acute lymphoblastic leukemia (ALL)
F Mohammad, AA Pandith, SUA Rasool, FR Guru… - Discover Oncology, 2024 - Springer
Background Fragile histidine triad (FHIT) has been documented to play a vital role in various
cancers including acute lymphoblastic leukemia (ALL). Keeping in view the plausible role of …
cancers including acute lymphoblastic leukemia (ALL). Keeping in view the plausible role of …
Disruption of pre-B-cell receptor signaling jams the WNT/β-catenin pathway and induces cell death in B-cell acute lymphoblastic leukemia cell lines
NS Saba, M Angelova, PA Lobelle-Rich, LS Levy - Leukemia research, 2015 - Elsevier
Targeting components of the B-cell receptor (BCR) pathway have dramatically improved
clinical outcomes in a variety of B-cell malignancies. Despite the well-documented …
clinical outcomes in a variety of B-cell malignancies. Despite the well-documented …
[HTML][HTML] Therapeutic approaches for relapsed/refractory adult acute lymphoblastic leukemia (ALL), a review on monoclonal antibodies and targeted therapies
Acute lymphoblastic leukemia (ALL) is the malignant transformation of lymphoid progenitors
that affects both children and adults. Although the outcome of pediatric patients has been …
that affects both children and adults. Although the outcome of pediatric patients has been …
[HTML][HTML] Regulation of small GTPase Rab20 by ikaros in B-cell acute lymphoblastic leukemia
JL Payne, C Song, Y Ding, PK Dhanyamraju… - International journal of …, 2020 - mdpi.com
Ikaros is a DNA-binding protein that regulates gene expression and functions as a tumor
suppressor in B-cell acute lymphoblastic leukemia (B-ALL). The full cohort of Ikaros target …
suppressor in B-cell acute lymphoblastic leukemia (B-ALL). The full cohort of Ikaros target …
[HTML][HTML] New insights on thyroid hormone mediated regulation of herpesvirus infections
RW Figliozzi, F Chen, SV Hsia - Cell & Bioscience, 2017 - Springer
Thyroid hormone (T 3) has been suggested to participate in the regulation of herpesvirus
replication during reactivation. Clinical observations and in vivo experiments suggest that T …
replication during reactivation. Clinical observations and in vivo experiments suggest that T …
ONTD induces growth arrest and apoptosis of human hepatoma Bel-7402 cells though a peroxisome proliferator-activated receptor γ-dependent pathway
J Tan, W Shen, W Shi, X Chen, D Sun, C Xu, Q Yan… - Toxicology in Vitro, 2017 - Elsevier
Abstract ONTD (3-Oxo-29-noroleana-1, 9 (11), 12-trien-2, 20-dicarbonitrile) is a novel
synthetic derivative of glycyrrhetinic acid (GA), which has been reported to exhibit anti …
synthetic derivative of glycyrrhetinic acid (GA), which has been reported to exhibit anti …
Targeting cancer stem cells and non-stem cancer cells: The potential of lipid-based nanoparticles
AF Cruz, NA Fonseca, V Moura… - Current …, 2017 - ingentaconnect.com
Background: Cancer stem cells (CSCs) have been described as a relevant contributor to
tumorigenicity, metastasis, tumor recurrence and drug resistance, making this cell …
tumorigenicity, metastasis, tumor recurrence and drug resistance, making this cell …
FHIT gene expression in acute lymphoblastic leukemia and its clinical significance
CA Malak, DM Elghanam… - Asian Pac J Cancer Prev, 2015 - journal.waocp.org
Background: To investigate the expression of the fragile histidine triad (FHIT) gene in acute
lymphoblastic leukemia and its clinical significance. Materials and Methods: The level of …
lymphoblastic leukemia and its clinical significance. Materials and Methods: The level of …
[HTML][HTML] TRIM37 interacts with PTEN to promote the growth of human T-cell acute lymphocytic leukemia cells through regulating PI3K/AKT pathway
H Qu, H Gao-Wa, Y Hou, M Ren, J Li, B Jing… - Frontiers in …, 2023 - frontiersin.org
Background TRIM37 has been reported to be associated with the tumorigenesis of cancers.
However, the role of TRIM37 in T-cell acute lymphoblastic leukemia (T-ALL) remains …
However, the role of TRIM37 in T-cell acute lymphoblastic leukemia (T-ALL) remains …