Background: Acute lymphoblastic leukemia (ALL), the most common childhood cancer with
a peak incidence in children from 2-5 years old, might be associated with poor prognosis …

EGFR: Receptor del EGF (del inglés epidermal growth factor receptor) FR: Factor de
regulación de la transcripción génica MMPs: Metaloproteasas de matriz (del inglés matrix …

CK2 and Akt (also known as PKB) are two antiapoptotic protein kinases, which
phosphorylate hundreds of substrates. While CK2 is constitutively active, Akt, under …

In this issue of Blood, Song et al show that tumor suppressor activity of Ikaros is achieved
though repression of cell cycle and phosphatidylinositol-3 (PI3) kinase pathway genes and …

Background: Casein Kinase 2 (CK2) is a Ser/Thr protein kinase that coregulates a great
number of signalling pathways in the cell. It is involved in cell cycle regulation and cell …

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive childhood hematological
malignancy. Despite the many improvements made in the treatment of T-ALL, it remains a …

Leucemia linfoblástica aguda (LLA) é o cancro mais frequente em pacientes pediátricos
sendo caracterizados por um crescimento anormal de linfócitos imaturos que se inicia na …

Introduction: Acute lymphoblastic leukemia (ALL) is the most common malignancy found in
the pediatrics with the peak prevalence between the ages of 2 and 5 years. The constitutive …

Die akute lymphatische Leukämie (ALL) ist die häufigste Krebserkrankung und zugleich die
häufigste krebsbedingte Todesursache im Kindesalter. Der PI3K/AKT/mTOR-Signalweg liegt …