[HTML][HTML] Unraveling the multifaceted nature of CD8 T cell exhaustion provides the molecular basis for therapeutic T cell reconstitution in chronic hepatitis B and C

V Barili, A Vecchi, M Rossi, I Montali, C Tiezzi, A Penna… - Cells, 2021 - mdpi.com
In chronic hepatitis B and C virus infections persistently elevated antigen levels drive CD8+
T cells toward a peculiar differentiation state known as T cell exhaustion, which poses …

[HTML][HTML] An angel or a devil? Current view on the role of CD8+ T cells in the pathogenesis of myasthenia gravis

Y Peng, H Yang, Q Chen, H Jin, Y Xue, M Du… - Journal of Translational …, 2024 - Springer
Background Myasthenia gravis (MG) and the experimental autoimmune MG (EAMG) animal
model are characterized by T-cell-induced and B-cell-dominated autoimmune diseases that …

Role of CXCR5+ CD8+ T cells in human hepatitis B virus infection

J Zhou, X He, Y Ou, S Peng, D Li, Q Zhou… - Journal of Viral …, 2023 - Wiley Online Library
The replication of HBV in hepatocytes can be effectively inhibited by lifelong antiviral
therapy. Because of the long‐term presence of HBV reservoirs, the virus rebound frequently …