The association of female and male infertility with telomere length

E Vasilopoulos, P Fragkiadaki… - International …, 2019 - spandidos-publications.com
Telomere length (TL) has long been associated with aging, as telomeres serve as protective
caps of chromosomes, and are thus deeply involved in the preservation of genome integrity …

Oxidative stress and reproductive function: Sperm telomeres, oxidative stress, and infertility

A Moazamian, P Gharagozloo, RJ Aitken… - …, 2022 - rep.bioscientifica.com
In brief Oxidative stress is recognized as an underlying driving factor of both telomere
dysfunction and human subfertility/infertility. This review briefly reassesses telomere integrity …

TERRA beyond cancer: the biology of telomeric repeat‐containing RNAs in somatic and germ cells

J Rivosecchi, E Cusanelli - Frontiers in Aging, 2023 - frontiersin.org
The telomeric noncoding RNA TERRA is a key component of telomeres and it is widely
expressed in normal as well as cancer cells. In the last 15 years, several publications have …

Telomerase activity and telomere length in male germ cells

S Ozturk - Biology of reproduction, 2015 - academic.oup.com
Telomeres are located at the outermost ends of all eukaryotic chromosomes and provide for
the maintenance of genomic stability and integrity during the life span of organisms. The …

Early‐life influences on obesity: from preconception to adolescence

ML Wahlqvist, SA Krawetz, NS Rizzo… - Annals of the New …, 2015 - Wiley Online Library
The double burden of under‐and overnutrition profoundly affects human health globally.
According to the World Health Organization, obesity and diabetes rates have almost …

Telomere dynamics throughout spermatogenesis

HE Fice, B Robaire - Genes, 2019 - mdpi.com
Telomeres are repeat regions of DNA that cap either end of each chromosome, thereby
providing stability and protection from the degradation of gene-rich regions. Each cell …

A single-cell assay for telomere DNA content shows increasing telomere length heterogeneity, as well as increasing mean telomere length in human spermatozoa …

DMF Antunes, KH Kalmbach, F Wang… - Journal of assisted …, 2015 - Springer
Purpose The effect of age on telomere length heterogeneity in men has not been studied
previously. Our aims were to determine the relationship between variation in sperm telomere …

Strategies for meiotic sex chromosome dynamics and telomeric elongation in Marsupials

L Marín-Gual, L González-Rodelas, G Pujol… - PLoS …, 2022 - journals.plos.org
During meiotic prophase I, homologous chromosomes pair, synapse and recombine in a
tightly regulated process that ensures the generation of genetically variable haploid …

Telomere length and telomerase activity during folliculogenesis in mammals

EG Kosebent, F Uysal, S Ozturk - Journal of Reproduction and …, 2018 - jstage.jst.go.jp
Telomeres are repetitive non-coding DNA sequences located at the ends of chromosomes
in eukaryotic cells. Their most important function is to protect chromosome ends from being …

Telomere homeostasis in mammalian germ cells: a review

R Reig-Viader, M Garcia-Caldés, A Ruiz-Herrera - Chromosoma, 2016 - Springer
Telomeres protect against genome instability and participate in chromosomal movements
during gametogenesis, especially in meiosis. Thus, maintaining telomere structure and …