Therapeutic vaccines for HPV-associated malignancies

C Smalley Rumfield, N Roller, ST Pellom… - ImmunoTargets and …, 2020 - Taylor & Francis
Human papillomavirus (HPV)-related malignancies are responsible for almost all cases of
cervical cancer in women, and over 50% of all cases of head and neck carcinoma …

[HTML][HTML] Human papilloma virus: A review study of epidemiology, carcinogenesis, diagnostic methods, and treatment of all HPV-related cancers

M Soheili, H Keyvani, M Soheili… - Medical journal of the …, 2021 - ncbi.nlm.nih.gov
Background: Human papillomavirus (HPV) infection is considered as the most common viral
sexually transmitted infection worldwide. This poses an increasingly interdisciplinary …

Resveratrol inhibits the progression of cervical cancer by suppressing the transcription and expression of HPV E6 and E7 genes

X Sun, P Fu, L Xie, S Chai, Q Xu… - International …, 2021 - spandidos-publications.com
Resveratrol is a representative polyphenol of diet‑derived putative cancer chemopreventive
agents, which have attracted increasing interest in the cancer chemoprevention community …

Porphyromonas gingivalis Promotes the Proliferation and Migration of Esophageal Squamous Cell Carcinoma through the miR-194/GRHL3/PTEN/Akt Axis

G Liang, H Wang, H Shi, M Zhu, J An, Y Qi… - ACS infectious …, 2020 - ACS Publications
Recent studies have revealed that Porphyromonas gingivalis is closely related to the
occurrence and progression of esophageal squamous cell carcinoma (ESCC). However, the …

Hydroxypropyl-β-Cyclodextrin-Complexed Resveratrol Enhanced Antitumor Activity in a Cervical Cancer Model: In Vivo Analysis

X Hao, X Sun, H Zhu, L Xie, X Wang, N Jiang… - Frontiers in …, 2021 - frontiersin.org
Trans-resveratrol (RES) exhibits a wide range of biological activities. Various
methodological approaches have been established to improve the pharmacokinetic …

Co-Delivery of p53 Restored and E7 Targeted Nucleic Acids by Poly (Beta-Amino Ester) Complex Nanoparticles for the Treatment of HPV Related Cervical Lesions

J Xiong, G Li, X Mei, J Ding, H Shen, D Zhu… - Frontiers in …, 2022 - frontiersin.org
The p53 gene has the highest mutation frequency in tumors, and its inactivation can lead to
malignant transformation, such as cell cycle arrest and apoptotic inhibition. Persistent high …

APOBEC3B is overexpressed in cervical cancer and promotes the proliferation of cervical cancer cells through apoptosis, cell cycle, and p53 pathway

Z Wei, J Gan, X Feng, M Zhang, Z Chen, H Zhao… - Frontiers in …, 2022 - frontiersin.org
Objective APOBEC3B (A3B), a member of the APOBEC family of cytidine deaminases, has
been gradually regarded as a key cancerous regulator. However, its expression and …

Ferroptosis: Mechanism and potential applications in cervical cancer

X Chang, J Miao - Frontiers in Molecular Biosciences, 2023 - frontiersin.org
Ferroptosis is a distinct form of cell death mechanism different from the traditional ones.
Ferroptosis is characterized biochemically by lipid peroxidation, iron accumulation, and …

An overview of angiogenesis and chemical and physiological angiogenic factors: short review

M Sedighi, M Namdari, P Mahmoudi - Journal of Chemical Health …, 2023 - eprints.lums.ac.ir
Angiogenesis refers to the formation of new blood vessels from existing ones, which can
occur in both physiologic and pathologic conditions. Lack of tissue oxygen is the main …

Cobimetinib sensitizes cervical cancer to paclitaxel via suppressing paclitaxel-induced ERK activation

Y Liu, R Zhao, X Qin, X Mao, Q Li, S Fang - Pharmacology, 2022 - karger.com
Introduction: Chemoresistance remains the main cause of treatment failure in cervical
cancer and novel therapeutic strategies are required. Cobimetinib, a potent yet selective …