Dietary polyphenols in chemoprevention and synergistic effect in cancer: Clinical evidences and molecular mechanisms of action

S Patra, B Pradhan, R Nayak, C Behera, S Das… - Phytomedicine, 2021 - Elsevier
Background Epidemiological studies has revealed that a diet rich in fruits and vegetables
could lower the risk of certain cancers. In this setting, natural polyphenols are potent …

[HTML][HTML] Quercetin in the prevention and treatment of coronavirus infections: a focus on SARS-CoV-2

A Gasmi, PK Mujawdiya, R Lysiuk, M Shanaida… - Pharmaceuticals, 2022 - mdpi.com
The COVID-19 outbreak seems to be the most dangerous challenge of the third millennium
due to its highly contagious nature. Amongst natural molecules for COVID-19 treatment, the …

[HTML][HTML] Dietary polyphenols—Important non-nutrients in the prevention of chronic noncommunicable diseases. A systematic review

W Koch - Nutrients, 2019 - mdpi.com
The improvement of the social and economic conditions of society has eliminated the threat
of death from the majority of infectious diseases. However, the rapid progress of civilization …

Pharmacological activity of quercetin: an updated review

G Wang, Y Wang, L Yao, W Gu, S Zhao… - Evidence‐Based …, 2022 - Wiley Online Library
Quercetin, a natural flavonoid compound with a widespread occurrence throughout the plant
kingdom, exhibits a variety of pharmacological activities. Because of the wide spectrum of …

[HTML][HTML] Ferroptosis in colorectal cancer: Potential mechanisms and effective therapeutic targets

Y Wang, Z Zhang, W Sun, J Zhang, Q Xu, X Zhou… - Biomedicine & …, 2022 - Elsevier
Colorectal cancer (CRC) is a common malignant tumor characterized by unchecked division
and survival of abnormal cells in the colon or rectum with high morbidity and mortality …

ROS‐mediated cancer cell killing through dietary phytochemicals

S NavaneethaKrishnan, JL Rosales… - Oxidative medicine and …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) promote carcinogenesis by inducing genetic mutations,
activating oncogenes, and raising oxidative stress, which all influence cell proliferation …

Natural compounds against doxorubicin‐induced cardiotoxicity: a review on the involvement of Nrf2/ARE signaling pathway

F Yarmohammadi, R Rezaee… - Phytotherapy Research, 2021 - Wiley Online Library
Cardiotoxicity is the main concern for long‐term use of the doxorubicin (DOX). Reactive
oxygen species (ROS) generation leads to oxidative stress that significantly contributes to …

Epigallocatechin gallate inhibits the uridylate-specific endoribonuclease Nsp15 and efficiently neutralizes the SARS-CoV-2 strain

S Hong, SH Seo, SJ Woo, Y Kwon… - Journal of Agricultural …, 2021 - ACS Publications
SARS-CoV-2, the coronavirus strain that initiated the COVID-19 pandemic, and its
subsequent variants present challenges to vaccine development and treatment. As the …

[HTML][HTML] The potential anti-cancer effects of quercetin on blood, prostate and lung cancers: An update

N Lotfi, Z Yousefi, M Golabi, P Khalilian… - Frontiers in …, 2023 - frontiersin.org
Cancer is caused by abnormal proliferation of cells and aberrant recognition of the immune
system. According to recent studies, natural products are most likely to be effective at …

[HTML][HTML] Bax/Bcl-2 cascade is regulated by the EGFR pathway: Therapeutic targeting of non-small cell lung cancer

M Alam, S Alam, A Shamsi, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Non-small cell lung carcinoma (NSCLC) comprises 80%–85% of lung cancer cases. EGFR
is involved in several cancer developments, including NSCLC. The EGFR pathway …