Risk of major gastrointestinal bleeding with new vs conventional oral anticoagulants: a systematic review and meta-analysis

ZC Gu, AH Wei, C Zhang, XH Wang, L Zhang… - Clinical …, 2020 - Elsevier
Background & Aims There is controversy over whether use of non-vitamin K antagonist oral
anticoagulants (NOACs) associates with increased risk of major gastrointestinal bleeding …

Comparative effectiveness and safety of direct acting oral anticoagulants in nonvalvular atrial fibrillation for stroke prevention: a systematic review and meta-analysis

J Zhang, X Wang, X Liu, TB Larsen, DM Witt… - European Journal of …, 2021 - Springer
Purpose: To systematically review available evidence of indirect comparisons from RCTs
and direct comparisons from observational studies regarding the comparative effectiveness …

Effectiveness and safety of apixaban compared with rivaroxaban for patients with atrial fibrillation in routine practice: a cohort study

M Fralick, M Colacci, S Schneeweiss… - Annals of internal …, 2020 - acpjournals.org
Background: Apixaban and rivaroxaban are the most commonly prescribed direct oral
anticoagulants for adults with atrial fibrillation, but head-to-head data comparing their safety …

Comparison of dabigatran, rivaroxaban, and apixaban for effectiveness and safety in atrial fibrillation: a nationwide cohort study

OCW Rutherford, C Jonasson… - European Heart …, 2020 - academic.oup.com
Aims The aim of this study was to compare the risk of stroke or systemic embolism (SE) and
major bleeding in patients with atrial fibrillation (AF) using dabigatran, rivaroxaban, and …

Risk of major bleeding among users of direct oral anticoagulants combined with interacting drugs: a population‐based nested case–control study

Y Zhang, PC Souverein, H Gardarsdottir… - British journal of …, 2020 - Wiley Online Library
Aims To assess the association between concurrent use of potential pharmacokinetic or
pharmacodynamic interacting drugs and major bleeding among direct oral anticoagulant …

Comparative effectiveness and safety of non–vitamin K antagonist oral anticoagulants in atrial fibrillation patients

W Zhu, Z Ye, S Chen, D Wu, J He, Y Dong, GYH Lip… - Stroke, 2021 - Am Heart Assoc
Background and Purpose: Several observational studies have compared the effect of the
non–vitamin K antagonist oral anticoagulants to each other in patients with atrial fibrillation …

Meta-analysis comparing apixaban versus rivaroxaban for management of patients with nonvalvular atrial fibrillation

MA Mamas, S Batson, KG Pollock, S Grundy… - The American Journal of …, 2022 - Elsevier
To compare the efficacy and safety of apixaban and rivaroxaban for the prevention of stroke
in patients with nonvalvular atrial fibrillation (NVAF) by way of a meta-analysis informed by …

Head-to-head efficacy and safety of rivaroxaban, apixaban, and dabigatran in an observational nationwide targeted trial

Y Talmor-Barkan, NS Yacovzada… - European Heart …, 2023 - academic.oup.com
Aims The advantages of direct oral anticoagulants (DOACs) over warfarin are well
established in atrial fibrillation (AF) patients, however, studies that can guide the selection …

Comparative effectiveness and safety of direct oral anticoagulants in patients with atrial fibrillation: a systematic review and meta-analysis of observational studies

A Douros, M Durand, CM Doyle, S Yoon, P Reynier… - Drug safety, 2019 - Springer
Background There are no head-to-head randomized controlled trials comparing different
direct oral anticoagulants (DOACs). Thus, we systematically reviewed and meta-analyzed …

Effectiveness and safety of apixaban in over 3.9 million people with atrial fibrillation: a systematic review and meta-analysis

BJR Buckley, DA Lane, P Calvert, J Zhang… - Journal of clinical …, 2022 - mdpi.com
Background: There is a plethora of real-world data on the safety and effectiveness of direct-
acting oral anticoagulants (DOACs); however, study heterogeneity has contributed to …