Myricetin (MYR) is a flavonoid compound widely found in many natural plants including
bayberry. So far, MYR has been proven to have multiple biological functions and it is a …

Metabolic reprogramming has become a key focus for both immunologists and cancer
biologists, with exciting advances providing new insights into the mechanisms underlying …

TET proteins (methylcytosine dioxygenases) play an important role in the regulation of gene
expression. Dysregulation of their activity is associated with many serious pathogenic states …

Hypoxia has a significant impact on many physiological and pathological processes. Over
the recent years, its role in modulation of epigenetic remodelling has also become clearer. In …

The acknowledgment that pollutants might influence the epigenome raises serious concerns
regarding their long-term impact on the development of chronic diseases. The herbicide …

DNA methylation at the fifth position of cytosine (5mC) is one of the most studied epigenetic
mechanisms essential for the control of gene expression and for many other biological …

During preimplantation development, a wave of genome-wide DNA demethylation occurs to
acquire a hypomethylated genome of the blastocyst. As an essential epigenomic event …

Ten-Eleven-Translocase (TET) enzymes contribute to the regulation of the methylome via
successive oxidation of 5-methyl cytosine (5mC) to derivatives which can be actively …

Somatic cell nuclear transfer (SCNT) has been successfully used for cloning in a variety of
mammalian species. However, SCNT reprogramming efficiency is relatively low, in part due …

ABSTRACT HDAC6 is an essential factor in mouse oocyte maturation. However, the roles of
HDAC6 in porcine oocyte maturation are still unclear. Therefore, we analyzed the roles of …