Vascular injury markers associated with cognitive impairment in people with HIV on suppressive antiretroviral therapy

D Guha, V Misra, J Yin, M Horiguchi, H Uno… - AIDS, 2023 - journals.lww.com
Objective: Human immunodeficiency virus (HIV)-associated neurocognitive disorders
(HAND) remain prevalent despite viral suppression on antiretroviral therapy (ART). Vascular …

CSF Inflammation Markers Associated with asymptomatic viral escape in Cerebrospinal Fluid of HIV-Positive individuals on antiretroviral therapy

D Guha, V Misra, J Yin, D Gabuzda - Viruses, 2023 - mdpi.com
HIV establishes a viral reservoir in the CNS despite viral suppression in the blood on
antiretroviral therapy (ART). In a minority of people with HIV (PWH), HIV RNA is detectable in …

Recent advances in HIV-associated neurocognitive disorders: a focus on older adults and sub-Saharan Africa

SM Paddick… - Current Opinion in …, 2024 - journals.lww.com
Cognitive impairment remains a significant challenge in the care of people living with HIV
despite advances in treatment. Ongoing controversies exist around nomenclature and …

[HTML][HTML] HIV-1–infected T cell clones are shared across cerebrospinal fluid and blood during ART

M Wang, J Yoon, H Reisert, B Das, B Orlinick… - JCI insight, 2024 - ncbi.nlm.nih.gov
The central nervous system HIV reservoir is incompletely understood and is a major barrier
to HIV cure. We profiled people with HIV (PWH) and uninfected controls through single-cell …

CSF Extracellular Vesicle Aβ42 and Tau/Aβ42 Ratio Are Associated with Cognitive Impairment in Older People with HIV

D Guha, V Misra, S Chettimada, J Yin, D Gabuzda - Viruses, 2023 - mdpi.com
HIV-associated neurocognitive disorders (HAND) remain prevalent despite viral
suppression on antiretroviral therapy (ART). Older people with HIV (PWH) are also at risk for …

Cognitive impairment and neurocognitive profiles among people living with HIV and HIV-negative individuals older over 50 years: a comparison of IHDS, MMSE and …

P Chen, X Xin, S Xiao, H Liu, X Liu, N He… - Journal of …, 2024 - Springer
We aimed to examine the l differences in the assessment of neurocognitive impairment
(NCI) using cognitive screening tools between PLWH and HIV-negative individuals and …

Improving Care for People Aging with HIV: A Collaborative Quality Improvement Approach

D Belanger, J Wikiera, M Albarran, A Zhu… - Journal of Community …, 2024 - Springer
Nearly 60% of people with HIV in New York State are over 50 years of age. After town halls
and a statewide survey of long-term survivors, older people living with HIV, and their …

Antiretroviral therapy intensification for HIV-associated neurocognitive disorder?

BJ Brew, DB Clifford - AIDS, 2023 - journals.lww.com
The treatment of HIV-associated neurocognitive disorder (HAND) in the context of
antiretroviral therapy (ART) induced viral suppression is unclear, as is its pathogenesis. In …

Biotypes of Central Nervous System Complications in People Living With Human Immunodeficiency Virus (HIV): National Institute of Mental Health Perspectives on …

VR Rao, P Brouwers, J Joseph… - The Journal of …, 2023 - academic.oup.com
Despite effective suppressive antiretroviral therapy, central nervous system (CNS)
complications related to human immunodeficiency virus (HIV) remain a significant problem …

[PDF][PDF] HIV 动物模型在毒品滥用研究中的应用

王婵, 杨根梦, 刘柳, 王浩伟, 苗霖, 李怡… - 中国实验动物 …, 2023 - zgbjyx.cnjournals.com
目前, 毒品滥用及人类免疫缺陷病毒(human immunodeficiency virus, HIV) 感染的共病问题备受
关注. 毒品滥用是HIV 传播的促发因素之一, 其同样可加重HIV 感染者中枢神经系统的病毒载量 …