In 2004, the first American Heart Association scientific statement on “Air Pollution and
Cardiovascular Disease” concluded that exposure to particulate matter (PM) air pollution …

A short-term increase in fine particulate matter air pollution (PM2. 5) concentration increases
the risk for myocardial infarctions, strokes, and heart failure exacerbations. An important …

The systemic inflammatory response syndrome initiated by infection shares many features in
common with the trauma-induced systemic response. The toll-like receptors (TLRs) stand at …

Rationale: The NF-E2 related factor 2 (Nrf2)–antioxidant response element (ARE) pathway
is essential for protection against oxidative injury and inflammation including hyperoxia …

High-temperature, controlled incineration and thermal treatment of contaminated soils,
sediments, and wastes at Superfund sites are often preferred methods of remediation of …

Early recognition of patients at high risk of acute lung injury (ALI) is critical for successful
enrolment of patients in prevention strategies for this devastating syndrome. We aimed to …

Ultrafine coal fly-ash particles, defined here as those with diameters less than 0.5 μm,
typically comprise less than 1% of the total fly-ash mass. These particles are formed …

Epidemiologic studies have reported the association between fine particles (aerodynamic
diameter≤ 2.5 μm; PM2. 5) and health effects, but the immunological mechanisms are not …

Marked international differences in rates of asthma and allergies and the importance of
family history highlight the primacy of interactions between genetic variation and the …

Rationale: Increasing evidence suggests that tumor necrosis factor (TNF)-α plays a key role
in pulmonary injury caused by environmental ozone (O3) in animal models and human …