Inflammatory bowel disease (IBD) is an immune-mediated chronic inflammation of the
intestine, which can present in the form of ulcerative colitis (UC) or as Crohn's disease (CD) …

Duchenne muscular dystrophy (DMD) is a fatal muscle-wasting disease, caused by
mutations in the dystrophin gene, characterised by cycles of muscle degeneration …

Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin in muscle, and while
all patients share the primary gene and biochemical defect, there is considerable patient …

The difficulty of the molecular design and chemical synthesis of artificial sensing receptors
restricts their diagnostic and proteomic applications. Herein, we report a concept of …

miR-486 is a muscle-enriched microRNA, or “myomiR,” that has reduced expression
correlated with Duchenne muscular dystrophy (DMD). To determine the function of miR-486 …

Background: Edasalonexent is an orally administered small molecule designed to inhibit NF-
κB, which is activated from infancy in Duchenne muscular dystrophy and is central to …

Extensive biomarker discoveries for DMD have occurred in the past 7 years, and a vast array
of these biomarkers were confirmed in independent cohorts and across different …

Introduction Carbonic anhydrase (CA) is a key enzyme that mediates the reversible
hydration of carbon dioxide. Skeletal muscles contain high levels of the cytosolic isoform …

Dysregulated inflammation involving innate immune cells, particularly of the monocyte/
macrophage lineage, is a key contributor to the pathogenesis of Duchenne muscular …

Background Preterm birth (PTB)(< 37 completed weeks' gestation) is a pathological outcome
of pregnancy and a major global health problem. Babies born preterm have an elevated risk …