Image-guided small animal radiation research platforms allow more precise radiation
treatment. Commercially available small animal X-ray irradiators are often equipped with a …

Total marrow irradiation (TMI) has significantly improved radiation conditioning for
hematopoietic cell transplantation in hematologic diseases by reducing conditioning …

Objective. Intensity-modulated radiotherapy (IMRT) is widely used in clinical radiotherapy,
treating varying malignancies with conformal doses. As the test field for clinical translation …

Sickle cell disease (SCD) is a serious global health problem, and currently, the only curative
option is hematopoietic stem cell transplant (HCT). However, myeloablative total body …

Purpose The goal of this study is to investigate treatment planning of total marrow irradiation
(TMI) using intensity-modulated spot-scanning proton therapy (IMPT). The dosimetric …

Total marrow (lymph node) irradiation (TMI/TMLI) delivery requires more time than standard
radiotherapy treatments. The patient's extremities, through the joints, can experience large …

Objective. Accuracy and reproducibility in the measurement of radiation dose and
associated reporting are critically important for the validity of basic and preclinical …

Image-guided mouse irradiation is essential to understand interventions involving radiation
prior to human studies. Our objective is to employ Swin UNEt Transformers (Swin UNETR) to …

Total body irradiation (TBI) is a commonly used conditioning regimen for hematopoietic stem
cell transplant (HCT), but dose heterogeneity and long-term organ toxicity pose significant …

Background and purpose Graft-versus-host disease (GvHD) is a leading cause of non-
relapse mortality in patients undergoing allogeneic hematopoietic stem cell transplantation …