Extracellular vesicle analysis
A Hendrix, L Lippens, C Pinheiro, C Théry… - Nature Reviews …, 2023 - nature.com
Cells release small, phospholipid membrane-enclosed particles, collectively referred to as
extracellular vesicles (EVs), into their surroundings to enable intercellular communication …
extracellular vesicles (EVs), into their surroundings to enable intercellular communication …
Molecular profiling for precision cancer therapies
ER Malone, M Oliva, PJB Sabatini, TL Stockley… - Genome medicine, 2020 - Springer
The number of druggable tumor-specific molecular aberrations has grown substantially in
the past decade, with a significant survival benefit obtained from biomarker matching …
the past decade, with a significant survival benefit obtained from biomarker matching …
Exosome detection via the ultrafast-isolation system: EXODUS
Exosomes have shown great potential in disease diagnostics and therapeutics. However,
current isolation approaches are burdensome and suffer from low speed, yield and purity …
current isolation approaches are burdensome and suffer from low speed, yield and purity …
Liquid biopsy in prostate cancer management—Current challenges and future perspectives
Simple Summary Prostate cancer (PCa) is a widespread malignancy, representing the
second leading cause of cancer-related death in men. In the last years, liquid biopsy has …
second leading cause of cancer-related death in men. In the last years, liquid biopsy has …
Liquid biopsy in bladder cancer: State of the art and future perspectives
F Crocetto, B Barone, M Ferro, GM Busetto… - Critical Reviews in …, 2022 - Elsevier
Bladder cancer is the most common malignancy of the urinary tract. Cystoscopy represents
the gold standard in the diagnosis of suspicious bladder lesions. However, the procedure is …
the gold standard in the diagnosis of suspicious bladder lesions. However, the procedure is …
[HTML][HTML] Circulating RNAs in prostate cancer patients
Growing bodies of evidence have demonstrated that the identification of prostate cancer
(PCa) biomarkers in the patients' blood and urine may remarkably improve PCa diagnosis …
(PCa) biomarkers in the patients' blood and urine may remarkably improve PCa diagnosis …
Network approach in liquidomics landscape
D Santini, A Botticelli, A Galvano, M Iuliani… - Journal of Experimental …, 2023 - Springer
Tissue-based biopsy is the present main tool to explore the molecular landscape of cancer,
but it also has many limits to be frequently executed, being too invasive with the risk of side …
but it also has many limits to be frequently executed, being too invasive with the risk of side …
Current challenges and best practices for cell-free long RNA biomarker discovery
The analysis of biomarkers in biological fluids, also known as liquid biopsies, is seen with
great potential to diagnose complex diseases such as cancer with a high sensitivity and …
great potential to diagnose complex diseases such as cancer with a high sensitivity and …
Clinical relevance of extracellular vesicles in hematological neoplasms: from liquid biopsy to cell biopsy
In the era of precision medicine, liquid biopsy is becoming increasingly important in
oncology. It consists in the isolation and analysis of tumor-derived biomarkers, including …
oncology. It consists in the isolation and analysis of tumor-derived biomarkers, including …
Urinary exosomal microRNAs as potential non-invasive biomarkers in breast cancer detection
M Hirschfeld, G Rücker, D Weiß, K Berner… - Molecular Diagnosis & …, 2020 - Springer
Introduction Breast cancer (BC) is the most frequent malignant disease in women worldwide
and is therefore challenging for the healthcare system. Early BC detection remains a leading …
and is therefore challenging for the healthcare system. Early BC detection remains a leading …