Neutrophils are crucial elements of innate immune system, which assure host defense via a
range of effector functions, such as phagocytosis, degranulation, and NET formation. The …

Abstract Background This Obesity Medicine Association (OMA) Clinical Practice Statement
(CPS) is intended to provide clinicians an overview of type 2 diabetes mellitus (T2DM), an …

Parkinson disease (PD) is a severe neurodegenerative disorder that affects around 2% of
the population over 65 years old. It is characterized by the progressive loss of nigrostriatal …

Metformin is the most often prescribed drug for people with type 2 diabetes (T2D). More than
120 million patients with T2D use metformin worldwide. However, monotherapy fails to …

Diabetes mellitus (DM) is a metabolic disorder that is one of the most common health
problems in the world, primarily type 2 DM (T2DM). Metformin (MTF), as the first-line …

Aging attenuates the overall responsiveness of the immune system to eradicate pathogens.
The increased production of pro-inflammatory cytokines by innate immune cells under basal …

Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia due to persistent insulin
resistance, resulting in elevated blood glucose levels. Metformin is the most prescribed oral …

Type 2 diabetes is a chronic and progressive cardiometabolic disorder that affects more than
10% of adults worldwide and is a major cause of morbidity, mortality, disability, and high …

Introduction Type 2 diabetes mellitus (T2DM) is the ninth leading cause of mortality globally,
and the prevalence continues to rise. Among individuals with T2DM, over two-thirds of …

Metformin is the most widely used drug to treat type 2 diabetes. Monitoring spatial patterns of
metformin use could provide new insights into treatment of type 2 diabetes and the …