Multiple nanotechnological approaches using natural compounds for diabetes management

OA Stoleru, AF Burlec, C Mircea, MG Felea… - Journal of Diabetes & …, 2024 - Springer
Objectives Diabetes mellitus (DM) is a long-standing and non-transmissible endocrine
disease that generates significant clinical issues and currently affects approximately 400 …

[HTML][HTML] Effect of metformin and metformin/linagliptin on gut microbiota in patients with prediabetes

MLY Estrella, NR Daniel, EHD Armando, PM Cristian… - Scientific Reports, 2024 - nature.com
Lifestyle modifications, metformin, and linagliptin reduce the incidence of type 2 diabetes
(T2D) in people with prediabetes. The gut microbiota (GM) may enhance such interventions' …

[HTML][HTML] Relationship between metformin use and mortality in tuberculosis patients with diabetes: a nationwide cohort study

E Chung, D Jeong, J Mok, D Jeon… - The Korean Journal …, 2024 - ncbi.nlm.nih.gov
Methods This cohort study included patients who were registered as having TB in the
National Tuberculosis Surveillance System. The medical and death records of matched …

[HTML][HTML] Metformin-Associated Gastrointestinal Adverse Events Are Reduced by Probiotics: A Meta-Analysis

I Szymczak-Pajor, J Drzewoski, S Wenclewska… - Pharmaceuticals, 2024 - mdpi.com
Metformin, one of the most frequently used oral glucose-lowering drugs (GLDs), is
associated with the occurrence of gastrointestinal (GI) adverse events in approximately 20 …

Recent Advances in Polymer-Based Nanoformulations for Enhancing Oral Drug Delivery in Diabetes

SS Garg, R Dey, A Sharma, J Gupta - Journal of Drug Delivery Science and …, 2024 - Elsevier
Diabetes is a long-term metabolic disorder caused by issues with insulin production or
response in the body. This leads to high levels of glucose in the blood, which can cause …

[HTML][HTML] Post-Translational Modifications and Diabetes

C Sharma, A Hamza, E Boyle, D Donu, Y Cen - Biomolecules, 2024 - mdpi.com
Diabetes and its associated complications have increasingly become major challenges for
global healthcare. The current therapeutic strategies involve insulin replacement therapy for …

[HTML][HTML] Clinical Trial: Probiotics in Metformin Intolerant Patients with Type 2 Diabetes (ProGasMet)

K Nabrdalik, K Drożdż, H Kwiendacz… - Biomedicine & …, 2023 - Elsevier
Background For decades, metformin has been the drug of first choice in the management of
type 2 diabetes. However, approximately 2–13% of patients do not tolerate metformin due to …

[HTML][HTML] Mitigation of Insulin Resistance by Natural Products from a New Class of Molecules, Membrane-Active Immunomodulators

E Izbicka, RT Streeper - Pharmaceuticals, 2023 - mdpi.com
Insulin resistance (IR), accompanied by an impaired cellular glucose uptake, characterizes
diverse pathologies that include, but are not limited to, metabolic disease, prediabetes and …

Chlorpropamide-cyclodextrin inclusion complexes, theoretical basis of stability

SE Pérez-Figueroa, EA Galván-García… - Journal of Molecular …, 2024 - Elsevier
A study of the stability of inclusion complexes of chlorpropamide and α, β, γ, and HP-β
cyclodextrin, has been carried out using molecular dynamics simulations. The contribution of …

[HTML][HTML] Changes in the Sensitivity of MCF-7 and MCF-7/DX Breast Cancer Cells to Cytostatic in the Presence of Metformin

J Płonka-Czerw, L Żyrek, M Latocha - Molecules, 2024 - mdpi.com
Multidrug resistance is a serious problem in modern medicine and the reason for the failure
of various therapies. A particularly important problem is the occurrence of multidrug …