[HTML][HTML] Learning from prepandemic data to forecast viral escape
Effective pandemic preparedness relies on anticipating viral mutations that are able to
evade host immune responses to facilitate vaccine and therapeutic design. However, current …
evade host immune responses to facilitate vaccine and therapeutic design. However, current …
[HTML][HTML] Jointly modeling deep mutational scans identifies shifted mutational effects among SARS-CoV-2 spike homologs
Deep mutational scanning (DMS) is a high-throughput experimental technique that
measures the effects of thousands of mutations to a protein. These experiments can be …
measures the effects of thousands of mutations to a protein. These experiments can be …
SHIV-C109p5 NHP induces rapid disease progression in elderly macaques with extensive GI viral replication
ABSTRACT CCR5-tropic simian/human immunodeficiency viruses (SHIV) with clade C
transmitted/founder envelopes represent a critical tool for the investigation of HIV …
transmitted/founder envelopes represent a critical tool for the investigation of HIV …
popDMS infers mutation effects from deep mutational scanning data
Deep mutational scanning (DMS) experiments provide a powerful method to measure the
functional effects of genetic mutations at massive scales. However, the data generated from …
functional effects of genetic mutations at massive scales. However, the data generated from …
Deep generative models for biology: represent, predict, design
P Notin - 2023 - ora.ox.ac.uk
Deep generative models have revolutionized the field of artificial intelligence, fundamentally
changing how we generate novel objects that imitate or extrapolate from training data, and …
changing how we generate novel objects that imitate or extrapolate from training data, and …
Learning from pre-pandemic data to forecast viral antibody escape
S Gurev - 2023 - dspace.mit.edu
Effective pandemic preparedness relies on anticipating viral mutations that are able to
evade host immune responses in order to facilitate vaccine and therapeutic design …
evade host immune responses in order to facilitate vaccine and therapeutic design …
Association between polymorphisms (rs1800896, rs1800872, rs1800871) in IL-10 gene with human immunodeficiency virus 1-infected patients' susceptibility
H Tai, L Xiao, D Zhou, Y Mi, W Zhang, S Yang - 2020 - researchsquare.com
Background Interleukin-10 (IL-10) is considered to play a role in the human
immunodeficiency virus-1 (HIV-1) infections, and 3 common single nucleotide …
immunodeficiency virus-1 (HIV-1) infections, and 3 common single nucleotide …