[HTML][HTML] Small molecule metabolites: discovery of biomarkers and therapeutic targets

S Qiu, Y Cai, H Yao, C Lin, Y Xie, S Tang… - Signal Transduction and …, 2023 - nature.com
Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

A Lavelle, H Sokol - Nature reviews Gastroenterology & hepatology, 2020 - nature.com
A key role of the gut microbiota in the establishment and maintenance of health, as well as in
the pathogenesis of disease, has been identified over the past two decades. One of the …

Integration of GC–MS and LC–MS for untargeted metabolomics profiling

ÖC Zeki, CC Eylem, T Reçber, S Kır… - Journal of Pharmaceutical …, 2020 - Elsevier
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …

[HTML][HTML] Guide to metabolomics analysis: a bioinformatics workflow

Y Chen, EM Li, LY Xu - Metabolites, 2022 - mdpi.com
Metabolomics is an emerging field that quantifies numerous metabolites systematically. The
key purpose of metabolomics is to identify the metabolites corresponding to each biological …

Emerging applications of metabolomics in drug discovery and precision medicine

DS Wishart - Nature reviews Drug discovery, 2016 - nature.com
Metabolomics is an emerging'omics' science involving the comprehensive characterization
of metabolites and metabolism in biological systems. Recent advances in metabolomics …

Discerning the chemistry in individual organelles with small‐molecule fluorescent probes

W Xu, Z Zeng, JH Jiang, YT Chang… - Angewandte Chemie …, 2016 - Wiley Online Library
Principle has it that even the most advanced super‐resolution microscope would be futile in
providing biological insight into subcellular matrices without well‐designed fluorescent …

[HTML][HTML] Rhizosphere microbiome: Engineering bacterial competitiveness for enhancing crop production

A Kumar, A Dubey - Journal of Advanced Research, 2020 - Elsevier
Plants in nature are constantly exposed to a variety of abiotic and biotic stresses which limits
their growth and production. Enhancing crop yield and production to feed exponentially …

Actinobacteria: current research and perspectives for bioremediation of pesticides and heavy metals

A Alvarez, JM Saez, JSD Costa, VL Colin, MS Fuentes… - Chemosphere, 2017 - Elsevier
Actinobacteria exhibit cosmopolitan distribution since their members are widely distributed
in aquatic and terrestrial ecosystems. In the environment they play relevant ecological roles …

Chemical and sensory characteristics of soy sauce: a review

C Diez-Simon, C Eichelsheim, R Mumm… - Journal of Agricultural …, 2020 - ACS Publications
Soy sauce is a fermented product, and its flavor is a complex mixture of individual senses
which, in combination, create a strong palatable condiment for many Eastern and Western …

[HTML][HTML] To metabolomics and beyond: a technological portfolio to investigate cancer metabolism

F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …