ART failure: oocyte contributions to unsuccessful fertilization

JE Swain, TB Pool - Human reproduction update, 2008 - academic.oup.com
BACKGROUND The complexity of fertilization failure during assisted reproductive
technologies (ART) is often under-appreciated, as this failure can occur at any number of …

Metabolic control of oocyte development: linking maternal nutrition and reproductive outcomes

L Gu, H Liu, X Gu, C Boots, KH Moley… - Cellular and molecular life …, 2015 - Springer
Obesity, diabetes, and related metabolic disorders are major health issues worldwide. As
the epidemic of metabolic disorders continues, the associated medical co-morbidities …

[HTML][HTML] Characterization of metabolic patterns in mouse oocytes during meiotic maturation

L Li, S Zhu, W Shu, Y Guo, Y Guan, J Zeng, H Wang… - Molecular cell, 2020 - cell.com
Well-balanced and timed metabolism is essential for making a high-quality egg. However,
the metabolic framework that supports oocyte development remains poorly understood …

[PDF][PDF] Metabolism throughout follicle and oocyte development in mammals

E Collado-Fernandez, HM Picton, R Dumollard - Int J Dev Biol, 2012 - researchgate.net
Metabolic studies of mammalian embryos started with the development of in vitro culture
systems more than 40 years ago. More recently, metabolic studies have begun to shed light …

Metabolism of radiolabeled glucose by mouse oocytes and oocyte-cumulus cell complexes

SM Downs, AM Utecht - Biology of reproduction, 1999 - academic.oup.com
This study was carried out to examine the metabolism of [1-14C]-,[6-14C]-, and [5-3H]
glucose by oocyte-cumulus cell complexes (OCC) and denuded oocytes (DO) and to test the …

Cumulus cells of oocyte‐cumulus complexes secrete a meiosis‐activating substance when stimulated with FSH

AG Byskov, CY Andersen, A Hossaini… - Molecular …, 1997 - Wiley Online Library
The effect of the different follicular cell types on resumption of meiosis was studied during
stimulation with FSH. Cumulus enclosed oocytes (CEO), denuded oocytes (DO), and …

Meiotic induction in cumulus cell-enclosed mouse oocytes: involvement of the pentose phosphate pathway

SM Downs, PG Humpherson… - Biology of …, 1998 - academic.oup.com
In this study we tested the hypothesis that the pentose phosphate pathway (PPP)
participates in the meiotic induction of mouse oocytes. The electron acceptors methylene …

[HTML][HTML] Effects of glucose metabolism during in vitro maturation on cytoplasmic maturation of mouse oocytes

HL Xie, YB Wang, GZ Jiao, DL Kong, Q Li, H Li… - Scientific reports, 2016 - nature.com
Although there are many reports on the effect of glucose metabolism on oocyte nuclear
maturation, there are few studies on its effect on ooplasmic maturation. By manipulating …

Metabolism of glucose, pyruvate, and glutamine during the maturation of oocytes derived from pre‐pubertal and adult cows

TE Steeves, DK Gardner - Molecular Reproduction and …, 1999 - Wiley Online Library
The aim of the study was to compare the energy metabolism of oocytes from pre‐pubertal (2
to 3 months) and adult cows during maturation, to identify the cause of poor developmental …

Prematuration with cyclic adenosine monophosphate modulators alters cumulus cell and oocyte metabolism and enhances developmental competence of in vitro …

HT Zeng, D Richani, ML Sutton-McDowall… - Biology of …, 2014 - academic.oup.com
Oocyte in vitro maturation (IVM) is an important assisted reproductive technology and
research tool. The adoption of IVM into routine clinical practice has been hindered by its …