Tackling antimicrobial resistance across sub-Saharan Africa: Current challenges and implications for the future

B Godman, A Egwuenu, E Wesangula… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Antimicrobial resistance (AMR) is a concern as this increases morbidity,
mortality, and costs, with sub-Saharan Africa having the highest rates globally. Concerns …

[HTML][HTML] Prevention of antimicrobial resistance in sub-Saharan Africa: What has worked? What still needs to be done?

P Moyo, E Moyo, D Mangoya, M Mhango… - Journal of Infection and …, 2023 - Elsevier
Antibiotics help in preventing and treating infections and increasing life expectancy globally.
Globally, many people's lives are being threatened by the emergence of antimicrobial …

Sepsis—A retrospective cohort study of bloodstream infections

B Santella, V Folliero, GM Pirofalo, E Serretiello… - Antibiotics, 2020 - mdpi.com
Bloodstream infections (BSIs) are among the leading causes of morbidity and mortality
worldwide, among infectious diseases. Local knowledge of the main bacteria involved in …

Point prevalence survey of antibiotic use and resistance at a referral hospital in Kenya: findings and implications

C Okoth, S Opanga, F Okalebo, M Oluka… - Hospital …, 2018 - Taylor & Francis
Background and aims: A substantial amount of antibiotic use in hospitals may be
inappropriate, potentially leading to the development and spread of antibiotic resistance …

A systematic review: the current status of carbapenem resistance in East Africa

K Ssekatawa, DK Byarugaba, E Wampande, F Ejobi - BMC research notes, 2018 - Springer
Objective In this systematic review, we present the molecular epidemiology and knowledge
gaps of the carbapenem resistance in East Africa as well as the future probable research …

Antimicrobial Resistance and Virulence Characteristics of Klebsiella pneumoniae Isolates in Kenya by Whole-Genome Sequencing

A Muraya, C Kyany'a, S Kiyaga, HJ Smith, C Kibet… - Pathogens, 2022 - mdpi.com
Klebsiella pneumoniae is a globally significant opportunistic pathogen causing healthcare-
associated and community-acquired infections. This study examined the epidemiology and …

Prevalence and outcome of bloodstream infections due to third-generation cephalosporin-resistant Enterobacteriaceae in sub-Saharan Africa: a systematic review

R Lester, P Musicha, N Van Ginneken… - Journal of …, 2020 - academic.oup.com
Background The prevalence of bacterial bloodstream infections (BSIs) in sub-Saharan Africa
(sSA) is high and antimicrobial resistance is likely to increase mortality from these infections …

Environmental contamination across multiple hospital departments with multidrug-resistant bacteria pose an elevated risk of healthcare-associated infections in …

E Odoyo, D Matano, F Tiria, M Georges… - … Resistance & Infection …, 2023 - Springer
Abstract Background Healthcare-associated infections (HAIs) are often caused by multidrug-
resistant (MDR) bacteria contaminating hospital environments which can cause outbreaks …

Association of Antibiotic Resistance, Cell Adherence, and Biofilm Production with the Endemicity of Nosocomial Klebsiella pneumoniae

MD Alcántar-Curiel… - BioMed research …, 2018 - Wiley Online Library
Klebsiella pneumoniae is a leading cause of multiple nosocomial infections, some of which
are associated with high mortality. The increasing prevalence of antibiotic‐resistant strains …

Review and mapping of carbapenem-resistant Enterobacteriaceae in Africa: using diverse data to inform surveillance gaps

EA Mitgang, DM Hartley, MD Malchione, M Koch… - International journal of …, 2018 - Elsevier
Carbapenem-resistant Enterobacteriaceae (CRE) are among the most difficult to treat
emerging multidrug-resistant organisms. Major limitations exist in surveillance needed to …