A comprehensive review on the emerging role of long non-coding RNAs in the regulation of NF-κB signaling in inflammatory lung diseases
Public health globally faces significant risks from conditions like acute respiratory distress
syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and various …
syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and various …
[HTML][HTML] Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions
Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …
Molecular profile of metastasis, cell plasticity and EMT in pancreatic cancer: a pre-clinical connection to aggressiveness and drug resistance
Z Guo, M Ashrafizadeh, W Zhang, R Zou… - Cancer and metastasis …, 2024 - Springer
The metastasis is a multistep process in which a small proportion of cancer cells are
detached from the colony to enter into blood cells for obtaining a new place for metastasis …
detached from the colony to enter into blood cells for obtaining a new place for metastasis …
[HTML][HTML] LncRNA-miRNA axis in tumor progression and therapy response: An emphasis on molecular interactions and therapeutic interventions
Epigenetic factors are critical regulators of biological and pathological mechanisms and they
could interact with different molecular pathways. Targeting epigenetic factors has been an …
could interact with different molecular pathways. Targeting epigenetic factors has been an …
[HTML][HTML] Paclitaxel and docetaxel resistance in prostate cancer: Molecular mechanisms and possible therapeutic strategies
M Hashemi, MA Zandieh, Y Talebi… - Biomedicine & …, 2023 - Elsevier
Prostate cancer is among most malignant tumors around the world and this urological tumor
can be developed as result of genomic mutations and their accumulation during progression …
can be developed as result of genomic mutations and their accumulation during progression …
Long noncoding RNA URB1-antisense RNA 1 (AS1) suppresses sorafenib-induced ferroptosis in hepatocellular carcinoma by driving ferritin phase separation
Sorafenib, a first-line molecular-target drug for advanced hepatocellular carcinoma (HCC),
has been shown to be a potent ferroptosis inducer in HCC. However, we found that there …
has been shown to be a potent ferroptosis inducer in HCC. However, we found that there …
Noncoding RNA as an influential epigenetic modulator with promising roles in cancer therapeutics
L Roy, O Chatterjee, D Bose, A Roy, S Chatterjee - Drug Discovery Today, 2023 - Elsevier
The epigenetic landscape has an important role in cellular homeostasis and its deregulation
leads to cancer. Noncoding (nc) RNA networks function as major regulators of cellular …
leads to cancer. Noncoding (nc) RNA networks function as major regulators of cellular …
FGFR families: biological functions and therapeutic interventions in tumors
Q Liu, J Huang, W Yan, Z Liu, S Liu, W Fang - MedComm, 2023 - Wiley Online Library
There are five fibroblast growth factor receptors (FGFRs), namely, FGFR1–FGFR5. When
FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and …
FGFR binds to its ligand, namely, fibroblast growth factor (FGF), it dimerizes and …
Non-coding RNAs targeting notch signaling pathway in cancer: From proliferation to cancer therapy resistance
M Hashemi, S Hasani, S Hajimazdarany… - International journal of …, 2022 - Elsevier
Cancer is a challenging to treat disease with a high mortality rate worldwide, nevertheless
advances in science has led to a decrease in the number of death cases caused by cancer …
advances in science has led to a decrease in the number of death cases caused by cancer …
Molecular panorama of therapy resistance in prostate cancer: a pre-clinical and bioinformatics analysis for clinical translation
Prostate cancer (PCa) is a malignant disorder of prostate gland being asymptomatic in early
stages and high metastatic potential in advanced stages. The chemotherapy and surgical …
stages and high metastatic potential in advanced stages. The chemotherapy and surgical …