Exploiting the critical perioperative period to improve long-term cancer outcomes
M Horowitz, E Neeman, E Sharon… - Nature reviews Clinical …, 2015 - nature.com
Evidence suggests that the perioperative period and the excision of the primary tumour can
promote the development of metastases—the main cause of cancer-related mortality. This …
promote the development of metastases—the main cause of cancer-related mortality. This …
Regulation of inflammation in cancer by eicosanoids
Inflammation in the tumor microenvironment is now recognized as one of the hallmarks of
cancer. Endogenously produced lipid autacoids, locally acting small molecule lipid …
cancer. Endogenously produced lipid autacoids, locally acting small molecule lipid …
M2 macrophages induced by prostaglandin E2 and IL-6 from cervical carcinoma are switched to activated M1 macrophages by CD4+ Th1 cells
M Heusinkveld, PJ de Vos van Steenwijk… - The Journal of …, 2011 - journals.aai.org
Monocytes attracted by tumor-induced chronic inflammation differentiate to APCs, the type of
which depends on cues in the local tumor milieu. In this work, we studied the influence of …
which depends on cues in the local tumor milieu. In this work, we studied the influence of …
Molecular pathways: vasculogenic mimicry in tumor cells: diagnostic and therapeutic implications
DA Kirschmann, EA Seftor, KM Hardy, REB Seftor… - Clinical cancer …, 2012 - AACR
Tumor cell vasculogenic mimicry (VM) describes the functional plasticity of aggressive
cancer cells forming de novo vascular networks, thereby providing a perfusion pathway for …
cancer cells forming de novo vascular networks, thereby providing a perfusion pathway for …
[HTML][HTML] Tumor cell vasculogenic mimicry: from controversy to therapeutic promise
REB Seftor, AR Hess, EA Seftor, DA Kirschmann… - The American journal of …, 2012 - Elsevier
In 1999, The American Journal of Pathology published an article entitled “Vascular Channel
Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry,” by …
Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry,” by …
Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
Colon cancer affects millions of individuals in Western countries. Cannabidiol, a safe and
non-psychotropic ingredient of Cannabis sativa, exerts pharmacological actions (antioxidant …
non-psychotropic ingredient of Cannabis sativa, exerts pharmacological actions (antioxidant …
Anisotropic gold nanoparticles in biomedical applications
C Kohout, C Santi, L Polito - International journal of molecular sciences, 2018 - mdpi.com
Gold nanoparticles (AuNPs) play a crucial role in the development of nanomedicine,
principally due to their unique photophysical properties and high biocompatibility. The …
principally due to their unique photophysical properties and high biocompatibility. The …
Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets?
G O'callaghan, A Houston - British journal of pharmacology, 2015 - Wiley Online Library
Elevated expression of COX‐2 and increased levels of PGE2 are found in numerous
cancers and are associated with tumour development and progression. Although …
cancers and are associated with tumour development and progression. Although …
Pattern-recognition receptors and gastric cancer
N Castaño-Rodríguez, NO Kaakoush… - Frontiers in …, 2014 - frontiersin.org
Chronic inflammation has been associated with an increased risk of several human
malignancies, a classic example being gastric adenocarcinoma (GC). Development of GC is …
malignancies, a classic example being gastric adenocarcinoma (GC). Development of GC is …
Tumor cell vascular mimicry: Novel targeting opportunity in melanoma
MJC Hendrix, EA Seftor, REB Seftor, JT Chao… - Pharmacology & …, 2016 - Elsevier
Abstract In 1999, the American Journal of Pathology published an article, entitled “Vascular
channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry” by …
channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry” by …