Thrombus formation at high shear rates

LDC Casa, DN Ku - Annual review of biomedical engineering, 2017 - annualreviews.org
The final common pathway in myocardial infarction and ischemic stroke is occlusion of blood
flow from a thrombus forming under high shear rates in arteries. A high-shear thrombus …

Advances in Platelet-Dysfunction Diagnostic Technologies

I Yoon, JH Han, HJ Jeon - Biomolecules, 2024 - mdpi.com
The crucial role of platelets in hemostasis and their broad implications under various
physiological conditions underscore the importance of accurate platelet-function testing …

Effect of P2Y12 inhibitors on thrombus stability and endogenous fibrinolysis

N Spinthakis, M Farag, YX Gue, M Srinivasan… - Thrombosis research, 2019 - Elsevier
Although used routinely to reduce thrombotic events in patients with coronary disease, the
effects of P2Y 12 inhibitors on thrombus stability and endogenous fibrinolysis are largely …

Prevention of thrombotic disorders by antithrombotic diet and exercise: evidence by using global thrombosis tests

J Yamamoto, Y Ijiri, H Ikarugi, K Otsui, N Inoue… - Future science …, 2018 - Taylor & Francis
Prevention of thrombotic disorders has priority over treatment. There are only two
pathologically relevant tests which are suitable for measuring the overall thrombotic status …

Overwork accelerates thrombotic reaction: implications for the pathogenesis of Karoshi

K Otsui, J Yamamoto, N Inoue - Journal of thrombosis and thrombolysis, 2018 - Springer
Work-related stressors are potential causes of cardiovascular diseases (CVDs) and stroke;
however, the pathophysiological mechanisms by which occupational stress induces and …

Global thrombosis test: occlusion by coagulation or SIPA?

V Clavería, PJ Yang, MT Griffin, DN Ku - TH Open, 2021 - thieme-connect.com
The global thrombosis test (GTT) is a point of care device that tests thrombotic and
thrombolytic status. The device exposes whole blood flow to a combination of both high and …

Reevaluation of antithrombotic fruits and vegetables: great variation between varieties

J Yamamoto, Y Ijiri, Y Tamura, M Iwasaki… - Drug Discoveries & …, 2016 - jstage.jst.go.jp
In the quest for prevention of atherothrombotic diseases, an antithrombotic diet may offer a
promising approach. The major stumbling block in finding an effective diet is the lack of …

[PDF][PDF] Diet of fruits and vegetables with experimental antithrombotic effect may be beneficial to humans in the prevention of arterial thrombotic diseases

Y Ijiri, H Ishii, J Yamamoto - Int. J. Drug Dev. Res, 2016 - researchgate.net
Prevention of arterial thrombotic disorders is a very important socioeconomic challenge. The
most convenient way of prevention could be by dietary means. In testing diets for …

Platelet function testing: a role for personalised therapy in coronary disease

M Farag, DA Gorog - Current Pharmaceutical Design, 2017 - ingentaconnect.com
Whilst there exist general guidelines regarding administration of antiplatelet therapy to
prevent thrombotic events in patients with cardiovascular disease, the optimal therapy for a …

Von Willebrand Factor and Platelet Aggregation: from Bench to Clinical Practice

KJ Ashworth, KA Thomas, SM Shea - Current Anesthesiology Reports, 2022 - Springer
Abstract Purpose of Review This review describes von Willebrand factor (VWF)-mediated
platelet function in inherited and acquired bleeding disorders, and current and novel …