Do the current guidelines for heart failure diagnosis and treatment fit with clinical complexity?

P Severino, A D'Amato, S Prosperi, A Dei Cas… - Journal of Clinical …, 2022 - mdpi.com
Heart failure (HF) is a clinical syndrome defined by specific symptoms and signs due to
structural and/or functional heart abnormalities, which lead to inadequate cardiac output …

Does the measurement of ejection fraction still make sense in the HFpEF framework? What recent trials suggest

A Palazzuoli, M Correale, M Iacoviello… - Journal of Clinical …, 2023 - mdpi.com
Left ventricular ejection fraction (LVEF) is universally accepted as a cardiac systolic function
index and it provides intuitive interpretation of cardiac performance. Over the last two …

Normal values of cardiac output and stroke volume according to measurement technique, age, sex, and ethnicity: results of the world alliance of societies of …

HN Patel, T Miyoshi, K Addetia, MP Henry… - Journal of the American …, 2021 - Elsevier
Background Assessment of cardiac output (CO) and stroke volume (SV) is essential to
understand cardiac function and hemodynamics. These parameters can be examined using …

Benefit from sacubitril/valsartan is associated with hemodynamic improvement in heart failure with reduced ejection fraction: An echocardiographic study

E Carluccio, FL Dini, R Bitto, M Ciccarelli… - International Journal of …, 2022 - Elsevier
Background Sacubitril/valsartan improves outcome in patients with heart failure (HF) with
reduced left ventricular (LV) ejection fraction (EF, HFrEF). However, little is known about …

Patient phenotype profiling using echocardiography and natriuretic peptides to personalise heart failure therapy

FL Dini, E Carluccio, S Ghio, NR Pugliese… - Heart Failure …, 2024 - Springer
Heart failure (HF) is a progressive condition with a clinical picture resulting from reduced
cardiac output (CO) and/or elevated left ventricular (LV) filling pressures (LVFP). The original …

Echocardiographic evaluation of left ventricular output in patients with heart failure: a per-beat or per-minute approach?

D Mele, G Pestelli, D Dal Molin, F Trevisan… - Journal of the American …, 2020 - Elsevier
Background Left ventricular (LV) output is a predictor of adverse outcome in patients with
heart failure. It can be evaluated using a per-beat approach, measuring stroke volume index …

Novel echocardiographic approach to hemodynamic phenotypes predicts outcome of patients hospitalized with heart failure

D Mele, G Pestelli, FL Dini, D Dal Molin… - Circulation …, 2020 - Am Heart Assoc
Background: Although in clinical practice heart failure (HF) patients are classified using left
ventricular ejection fraction (LVEF), this categorization is insufficient for prognosis, especially …

The conundrum of HFpEF definition: non-invasive assessment uncertainties and alternative diagnostic strategies

A Palazzuoli, MGD Buono, G Ruocco, S Caravita… - Current Problems in …, 2023 - Elsevier
Heart failure (HF) with preserved ejection fraction (HFpEF) is a heterogeneous syndrome
including several morphological phenotypes and varying pathophysiological mechanisms …

Exploring the Risk Factors of Sudden Cardiac Death Using an Electrocardiography and Medical Ultrasonography for the General Population Without a History of …

YY Chen, FP Chung, YJ Lin, KL Chien… - Circulation …, 2022 - jstage.jst.go.jp
Background: Most of the factors and prediction models of sudden cardiac death (SCD) have
been developed without considering the Asia population. The purpose of this study is to …

Right atrial pressure is associated with outcomes in patients with heart failure and indeterminate left ventricular filling pressure

D Mele, G Pestelli, D Dal Molin, V Smarrazzo… - Journal of the American …, 2020 - Elsevier
Background In a significant proportion of patients with left-sided heart failure (HF), left
ventricular filling pressure (LVFP) may not be estimated using echocardiography, so filling …