Mesenchymal stem cells (MSCs) have emerged as a promising tool for the treatment of
several neurodegenerative disorders, including Alzheimer's disease (AD). The main …

Neural stem cells give rise to new hippocampal neurons throughout adulthood, and defects
in neurogenesis may predispose an individual to mood disorders, such as major …

Considerable evidence suggests that adolescent exposure to delta-9-tetrahydrocanabinol
(THC), the psychoactive component in marijuana, increases the risk of developing …

We had previously shown that both locally produced endocannabinoids and
exocannabinoids, via cannabinoid receptor‐1 (CB1), are powerful inhibitors of human hair …

The immune-suppressive effects of cannabidiol (CBD) are attributed to the modulation of
essential immunological signaling pathways and receptors. Mechanistic understanding of …

Activation of G protein-coupled receptors results in multiple waves of signaling that are
mediated by heterotrimeric G proteins and the scaffolding proteins β-arrestin 1/2. Ligands …

Introduction: Cannabidiol (CBD) is the second most abundant Phytocannabinoid in
Cannabis extracts. CBD has a binding affinity for several cannabinoid and cannabinoid …

The mammalian (or mechanistic) target of rapamycin (mTOR) complex 1 (mTORC 1) is a
serine and threonine kinase that regulates cell growth, survival, and proliferation. mTORC 1 …

Smoking cannabis daily doubles an individual's risk of developing a psychotic disorder, yet
indicators of specific vulnerability have proved largely elusive. Genetic variation is one …

The cerebral ischemic reperfusion injury may leads to morbidity and mortality in patients.
phosphatidylinositol 3-kinase (PI3K) signaling pathway has been believed to work in …