[HTML][HTML] ncRNA-encoded peptides or proteins and cancer

J Wang, S Zhu, N Meng, Y He, R Lu, GR Yan - Molecular Therapy, 2019 - cell.com
Non-coding RNAs (ncRNAs) are unique RNA transcripts that have been widely identified in
the eukaryotic genome and have been shown to play key roles in the development of many …

[HTML][HTML] The dark proteome: translation from noncanonical open reading frames

BW Wright, Z Yi, JS Weissman, J Chen - Trends in Cell Biology, 2022 - cell.com
Omics-based technologies have revolutionized our understanding of the coding potential of
the genome. In particular, these studies revealed widespread unannotated open reading …

Database resources of the national genomics data center, China national center for bioinformation in 2023

Nucleic acids research, 2023 - academic.oup.com
Abstract The National Genomics Data Center (NGDC), part of the China National Center for
Bioinformation (CNCB), provides a family of database resources to support global academic …

NONCODEV5: a comprehensive annotation database for long non-coding RNAs

SS Fang, LL Zhang, JC Guo, YW Niu, Y Wu… - Nucleic acids …, 2018 - academic.oup.com
Abstract NONCODE (http://www. bioinfo. org/noncode/) is a systematic database that is
dedicated to presenting the most complete collection and annotation of non-coding RNAs …

[PDF][PDF] Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames

CL Sandmann, JF Schulz, J Ruiz-Orera, M Kirchner… - Molecular cell, 2023 - cell.com
All species continuously evolve short open reading frames (sORFs) that can be templated
for protein synthesis and may provide raw materials for evolutionary adaptation. We …

[PDF][PDF] A high-resolution map of human RNA translation

SP Chothani, E Adami, AA Widjaja, SR Langley… - Molecular cell, 2022 - cell.com
Translated small open reading frames (smORFs) can have important regulatory roles and
encode microproteins, yet their genome-wide identification has been challenging. We …

The small peptide world in long noncoding RNAs

SW Choi, HW Kim, JW Nam - Briefings in bioinformatics, 2019 - academic.oup.com
Long noncoding RNAs (lncRNAs) are a group of transcripts that are longer than 200
nucleotides (nt) without coding potential. Over the past decade, tens of thousands of novel …

Accurate annotation of human protein-coding small open reading frames

TF Martinez, Q Chu, C Donaldson, D Tan… - Nature chemical …, 2020 - nature.com
Functional protein-coding small open reading frames (smORFs) are emerging as an
important class of genes. However, the number of translated smORFs in the human genome …

Translation of noncoding RNAs and cancer

B Zhou, H Yang, C Yang, Y Bao, S Yang, J Liu, Y Xiao - Cancer letters, 2021 - Elsevier
The human genome contains thousands of noncoding RNAs (ncRNAs), which are thought to
lack open reading frames (ORFs) and cannot be translated. Some ncRNAs reportedly have …

LncSEA: a platform for long non-coding RNA related sets and enrichment analysis

J Chen, J Zhang, Y Gao, Y Li, C Feng… - Nucleic acids …, 2021 - academic.oup.com
Long non-coding RNAs (lncRNAs) have been proven to play important roles in
transcriptional processes and various biological functions. Establishing a comprehensive …