Neural tube defects are severe congenital malformations affecting around one in every 1000
pregnancies. An innovation in clinical management has come from the finding that closure of …

Congenital defects of neural tube closure (neural tube defects; NTDs) are among the
commonest and most severe disorders of the fetus and newborn. Disturbance of any of the …

A clear, engaging writing style, hundreds of full-color images, and new information
throughout make Volpe's Neurology of the Newborn, 6th Edition, an indispensable resource …

Physical environment, man‐made pollution, nutrition and their mutual interactions can be
major causes of human diseases. These disease determinants have distinct spatial …

Neural tube defects (NTDs) are severe congenital malformations affecting 1 in every 1000
pregnancies.'Open'NTDs result from failure of primary neurulation as seen in anencephaly …

Neural tube defects (NTDs) are common, severe congenital malformations whose causation
involves multiple genes and environmental factors. Although more than 200 genes are …

Changes in maternal nutrient availability due to diet or disease significantly increase the risk
of neural tube defects (NTDs). Because the incidence of metabolic disease continues to rise …

During the fifteen years since the bestselling first edition of Folate in Health and Disease
was published, there have been thousands of new research studies related to folate and its …

Correct notochord and neural tube (NT) formation is crucial to the development of the central
nervous system and midline structures. Integrated biochemical and biophysical signaling …

Studies of syndromic hydrocephalus have led to the identification of> 100 causative genes.
Even though this work has illuminated numerous pathways associated with hydrocephalus …