Abstract α-Thalassemia is an inherited blood disorder characterized by decreased synthesis
of α-globin chains that results in an imbalance of α and β globin and thus varying degrees of …

In this short review we have presented and discussed studies on pharmacogenomics (also
termed pharmacogenetics) of the drugs employed in the treatment of β-thalassemia or Sickle …

Background and Objectives: The effective management of chronic diseases, particularly
hereditary and rare diseases and thalassaemia, is an important indicator of the quality of …

Background Anemia is a significant contributor to the global disease burden, of which
thalassemia is the most common hereditary anaemic disease. Previous estimates were …

Therapy via the gene addition of the anti-sickling βAS3-globin transgene is potentially
curative for all β-hemoglobinopathies and therefore of particular clinical and commercial …

Thalassemia, a common inherited autosomal recessive disorder, is characterized by
inefficient or absent hemoglobin synthesis, resulting in various severities of anemia (1) …

Personalized medicine is defined as a medical model using the characterization of
individuals' phenotypes and genotypes (eg, molecular profiling, medical imaging, and …

Background: Thalassemia is an inherited disorder of hemoglobin (Hb) synthesis. Treatment
of thalassemia has not yet reached the level of cure. Globally, the management of …

Hemoglobinopathies are the most common single-gene disorders in humans. There are
1,424 variants of human hemoglobin described with 951 involving the β-globin gene …

Thalassemia, an autosomal recessive hematologic disease is becoming a serious health
problem worldwide with its high. prevalence and incidence (1). Thalassemia is a condition in …