Long-term consequences of traumatic brain injury: current status of potential mechanisms of injury and neurological outcomes

HM Bramlett, WD Dietrich - Journal of neurotrauma, 2015 - liebertpub.com
Traumatic brain injury (TBI) is a significant clinical problem with few therapeutic interventions
successfully translated to the clinic. Increased importance on the progressive, long-term …

Traumatic brain injury: a disease process, not an event

BE Masel, DS DeWitt - Journal of neurotrauma, 2010 - liebertpub.com
Traumatic brain injury (TBI) is seen by the insurance industry and many health care
providers as an “event.” Once treated and provided with a brief period of rehabilitation, the …

A decade of DTI in traumatic brain injury: 10 years and 100 articles later

MB Hulkower, DB Poliak… - American Journal …, 2013 - Am Soc Neuroradiology
The past decade has seen an increase in the number of articles reporting the use of DTI to
detect brain abnormalities in patients with traumatic brain injury. DTI is well-suited to the …

Traumatic brain injury as a disorder of brain connectivity

JP Hayes, ED Bigler, M Verfaellie - Journal of the International …, 2016 - cambridge.org
Objectives: Recent advances in neuroimaging methodologies sensitive to axonal injury
have made it possible to assess in vivo the extent of traumatic brain injury (TBI)-related …

Neuropathology of mild traumatic brain injury: relationship to neuroimaging findings

ED Bigler, WL Maxwell - Brain imaging and behavior, 2012 - Springer
Neuroimaging identified abnormalities associated with traumatic brain injury (TBI) are but
gross indicators that reflect underlying trauma-induced neuropathology at the cellular level …

Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here?

N Marklund, L Hillered - British journal of pharmacology, 2011 - Wiley Online Library
Traumatic brain injury (TBI) is the leading cause of death and disability in young adults.
Survivors of TBI frequently suffer from long‐term personality changes and deficits in …

Diffusion tensor imaging studies of mild traumatic brain injury: a meta-analysis

Y Aoki, R Inokuchi, M Gunshin, N Yahagi… - Journal of Neurology …, 2012 - jnnp.bmj.com
Objectives To assess the possibility that diffusion tensor imaging (DTI) can detect white
matter damage in mild traumatic brain injury (mTBI) patients via systematic review and meta …

[HTML][HTML] Traumatic brain injury, neuroimaging, and neurodegeneration

ED Bigler - Frontiers in human neuroscience, 2013 - frontiersin.org
Depending on severity, traumatic brain injury (TBI) induces immediate neuropathological
effects that in the mildest form may be transient but as severity increases results in neural …

Blood supply and vascular reactivity of the spinal cord under normal and pathological conditions: A review

NL Martirosyan, JS Feuerstein, N Theodore… - … of Neurosurgery: Spine, 2011 - thejns.org
The authors present a review of spinal cord blood supply, discussing the anatomy of the
vascular system and physiological aspects of blood flow regulation in normal and injured …

Are functional deficits in concussed individuals consistent with white matter structural alterations: combined FMRI & DTI study

K Zhang, B Johnson, D Pennell, W Ray… - Experimental Brain …, 2010 - Springer
There is still controversy in the literature whether a single episode of mild traumatic brain
injury (MTBI) results in short-term functional and/or structural deficits as well as any induced …