Chronic diabetic complications are classified as microvascular or macrovascular and
contribute to mortality and loss of quality of life. Hyperglycemia plays a critical role in the …

Objective. To facilitate the clinician's understanding of the basis and treatment of painful
diabetic neuropathy (PDN). Background. PDN is one of several clinical syndromes in …

Objective To evaluate the effects and safety of 300–600 mg α-lipoic acid (ALA) given iv for
diabetic peripheral neuropathy (DPN). Methods We searched the databases of Medline …

Mercury exposure is the second-most common cause of toxic metal poisoning. Public health
concern over mercury exposure, due to contamination of fish with methylmercury and the …

The nuclear factor-κB (NF-κB) family is comprised of DNA-binding protein factors that are
required for the transcription of most proinflammatory molecules, including adhesion …

Cardiac autonomic neuropathy (CAN) is a major complication of type 1 and type 2 diabetes
mellitus (T1DM and T2DM). The increased morbidity, cardiovascular and all-cause mortality …

Alpha-lipoic acid (ALA) is a natural compound with antioxidant and pro-oxidant properties
which has effects on the regulation of insulin sensitivity and insulin secretion. ALA is widely …

The morbidity caused by diabetes has traditionally been classified into macro-and
microvascular complications. Although macrovascular complications have received greater …

Diabetic neuropathies (DNs) are a heterogeneous group of disorders and present a wide
range of abnormalities. They are among the most common long-term complications of …

Objective To review the efficacy and safety of natural products commonly used for diabetes.
Data Sources English and Spanish-language journals retrieved through a MEDLINE search …