[HTML][HTML] Ion-doped brushite cements for bone regeneration

K Hurle, JM Oliveira, RL Reis, S Pina… - Acta biomaterialia, 2021 - Elsevier
Decades of research in orthopaedics has culminated in the quest for formidable yet
resorbable biomaterials using bioactive materials. Brushite cements most salient features …

Building osteogenic microenvironments with strontium-substituted calcium phosphate ceramics

B Wan, R Wang, Y Sun, J Cao, H Wang… - … in Bioengineering and …, 2020 - frontiersin.org
Bioceramics have experienced great development over the past 50 years. Modern
bioceramics are designed to integrate bioactive ions within ceramic granules to trigger living …

[HTML][HTML] Icariin self-crosslinked network functionalized strontium-doped bioceramic scaffolds synergistically enhanced the healing of osteoporotic bone defects

T Song, J Yang, P Liu, M Liu, D Li, Y Xiao… - Composites Part B …, 2022 - Elsevier
The regeneration of osteoporotic defects remains a great challenge in clinic, due to the
capacity of bone regeneration is seriously impaired and bone resorption is overactivated …

Local administration of aspirin with β-tricalcium phosphate/poly-lactic-co-glycolic acid (β-TCP/PLGA) could enhance osteoporotic bone regeneration

ZS Tao, XJ Wu, WS Zhou, X Wu, W Liao… - Journal of bone and …, 2019 - Springer
Composite materials β-tricalcium phosphate (β-TCP) and poly-lactic-co-glycolic acid (PLGA)
have achieved stable bone regeneration without cell transplantation in previous studies …

Hydrogel contained valproic acid accelerates bone-defect repair via activating Notch signaling pathway in ovariectomized rats

ZS Tao, TL Li, HG Xu, M Yang - Journal of Materials Science: Materials in …, 2022 - Springer
The purpose was to observe whether valproic acid (VPA) has a positive effect on bone-
defect repair via activating the Notch signaling pathway in an OVX rat model. The MC3T3-E1 …

Recent developments in strontium-based biocomposites for bone regeneration

S Zhang, Y Dong, M Chen, Y Xu, J Ping, W Chen… - Journal of Artificial …, 2020 - Springer
Recent advances in biomaterial designing techniques offer immense support to tailor
biomimetic scaffolds and to engineer the microstructure of biomaterials for triggering bone …

Adjuvant drug-assisted bone healing: Advances and challenges in drug delivery approaches

R Rothe, S Hauser, C Neuber, M Laube, S Schulze… - Pharmaceutics, 2020 - mdpi.com
Bone defects of critical size after compound fractures, infections, or tumor resections are a
challenge in treatment. Particularly, this applies to bone defects in patients with impaired …

[HTML][HTML] Aspirin modified strontium-doped β-tricalcium phosphate can accelerate the healing of femoral metaphyseal defects in ovariectomized rats

ZS Tao, WS Zhou, HG Xu, M Yang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
The purpose was to observe whether local administration Strontium (Sr) and Aspirin (Asp)
can enhance the efficacy of β-Tricalcium phosphate (β-TCP) in the treatment of osteoporotic …

Co-modified 3D printed β-tricalcium phosphate with magnesium and selenium promotes bone defect regeneration in ovariectomized rat

ZS Tao, TL Li, S Wei - Journal of Materials Science: Materials in Medicine, 2023 - Springer
Abstract Magnesium (Mg) and Selenium (Se) are essential elements for bone health and
have been studied extensively for its powerful osteogenesis and promoting bone …

Strontium based Astragalus polysaccharides promote osteoblasts differentiation and mineralization

Y Peng, F Ma, L Hu, Y Deng, W He, B Tang - International Journal of …, 2022 - Elsevier
Bone formation and repair represent a clinical challenge. In this work, we designed and
synthesized strontium Astragalus polysaccharide (APS-Sr), a novel polysaccharide …