Molecular pathways in sepsis pathogenesis: Recent advances and therapeutic avenues

TA Addissouky, IET El Sayed, MMA Ali… - Journal of Cellular …, 2024 - scientificarchives.com
Molecular Pathways in Sepsis Pathogenesis: Recent Advances and Therapeutic Avenues
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Practical Lessons on Antimicrobial Therapy for Critically Ill Patients

R Cusack, E Little, I Martin-Loeches - Antibiotics, 2024 - mdpi.com
Sepsis stands as a formidable global health challenge, with persistently elevated mortality
rates in recent decades. Each year, sepsis not only contributes to heightened morbidity but …

Interferon-Gamma-Release assay and absolute CD8 lymphocyte count for acquired immunosuppression monitoring in critically ill patients

MH Rahimi, F Venet, AC Lukaszewicz, E Peronnet… - Cytokine, 2024 - Elsevier
Guided biomarker-personalized immunotherapy is advancing rapidly as a means to
rejuvenate immune function in injured patients who are the most immunosuppressed. A …

Immunological alterations in the endothelial barrier: a new predictive and therapeutic paradigm for sepsis

J Feng, L Liu, J Liu, J Wang - Expert Review of Clinical …, 2024 - Taylor & Francis
Introduction Despite the fact incidence and mortality vary widely among regions, sepsis
remains a major cause of morbidity and cost worldwide. The importance of the endothelial …

[PDF][PDF] Towards personalized care: Unraveling the genomic and molecular basis of sepsis-induced respiratory complications

TA Addissouky, IET El Sayed, MMA Ali, MHS Alubiady… - 2024 - researchgate.net
Background Sepsis, a life-threatening syndrome characterized by organ dysfunction, is a
global health concern with alarmingly high morbidity and mortality rates [1]. In understanding …

Sepsis phenotypes, subphenotypes, and endotypes: are they ready for bedside care?

SJ Scherger, AC Kalil - Current Opinion in Critical Care - journals.lww.com
Sepsis therapies including care bundles, fluid resuscitation, and source control procedures
may be better guided by validated phenotypes than universal application. Novel biomarkers …