The emerging threat of (micro) thrombosis in COVID-19 and its therapeutic implications

JD McFadyen, H Stevens, K Peter - Circulation research, 2020 - Am Heart Assoc
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing global pandemic has presented a health emergency of unprecedented …

Is acetylsalicylic acid a safe and potentially useful choice for adult patients with COVID-19?

V Bianconi, F Violi, F Fallarino, P Pignatelli… - Drugs, 2020 - Springer
Abstract Severe Acute Respiratory Syndrome–Coronavirus-2 is responsible for the current
pandemic that has led to more than 10 million confirmed cases of Coronavirus Disease-19 …

Advance in the management of sepsis-induced coagulopathy and disseminated intravascular coagulation

T Iba, JH Levy, A Raj, TE Warkentin - Journal of clinical medicine, 2019 - mdpi.com
Coagulopathy commonly occurs in sepsis as a critical host response to infection that can
progress to disseminated intravascular coagulation (DIC) with an increased mortality …

Platelet activation in critically ill COVID-19 patients

N Yatim, J Boussier, R Chocron, J Hadjadj… - Annals of intensive …, 2021 - Springer
Background Microvascular, arterial and venous thrombotic events have been largely
described during severe coronavirus disease 19 (COVID-19). However, mechanisms …

Early use of high-dose vitamin C is beneficial in treatment of sepsis

SJ Lv, GH Zhang, JM Xia, H Yu, F Zhao - Irish Journal of Medical Science …, 2021 - Springer
Purpose Vitamin C has shown benefits in patients with sepsis in addition to standard therapy
recently. However, further evidence is required to verify the efficacy of vitamin C in clinical …

Significance of MPV, RDW and PDW with the Severity and Mortality of COVID-19 and Effects of Acetylsalicylic Acid Use

F Aydınyılmaz, E Aksakal… - Clinical and Applied …, 2021 - journals.sagepub.com
We aimed to investigate association between mean platelet volume (MVP), platelet
distribution width (PDW) and red cell distribution width (RDW) and mortality in patients with …

Management of patients on antithrombotic therapy with severe infections: a joint clinical consensus statement of the ESC Working Group on Thrombosis, the ESC …

B Gigante, JH Levy, E van Gorp, A Bartoloni… - European heart …, 2023 - academic.oup.com
Patients with severe infections and a pre-existing indication for antithrombotic therapy, ie
antiplatelet agents, anticoagulant drugs, or their combinations, require integrated clinical …

[HTML][HTML] Potential role of herbal medicines as a novel approach in sepsis treatment

J Usmani, T Khan, R Ahmad, M Sharma - Biomedicine & Pharmacotherapy, 2021 - Elsevier
The growing number of deaths related to sepsis has become a major concern for past few
years. Sepsis is a complex pathological reactions that is explained by series of host …

Alterations in platelets during SARS-CoV-2 infection

M Brambilla, P Canzano, A Becchetti, E Tremoli… - Platelets, 2022 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) is a pandemic syndrome caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. SARS-CoV-2 infection …

Pre-admission acetylsalicylic acid therapy and impact on in-hospital outcome in COVID-19 patients: The ASA-CARE study

A Sisinni, L Rossi, A Battista, E Poletti, F Battista… - International Journal of …, 2021 - Elsevier
Background Patients with coronavirus disease 2019 (COVID-19) exhibit high thrombotic risk.
The evidence on a potential independent prognostic role of antiplatelet treatment in those …