Glioblastoma (GBM) is the most deadly type of malignant brain tumor, despite extensive
molecular analyses of GBM cells. In recent years, the tumor microenvironment (TME) has …

Gliomas are the most common primary brain tumors in adults. Despite the fact that they are
relatively rare, they cause significant morbidity and mortality. High-grade gliomas or …

In recent years, the endocannabinoid system has received great interest as a potential
therapeutic target in numerous pathological conditions. Cannabinoids have shown an …

Gliomas are the most common and challenging malignancies of the central nervous system
(CNS), due to their infiltrative nature, tendency to recurrence, and poor response to …

Glioblastoma (GBM) is the most common and malignant primary brain tumor in adults
associated with a poor survival. Current standard of care consists of surgical resection …

Glioblastoma (GBM) is the most common and malignant primary brain cancer in adults.
Without treatment the mean patient survival is approximately 6 months, which can be …

Brain cancer remains the deadliest cancer. The blood–brain barrier (BBB) is impenetrable to
most drugs and is a complex 3D network of multiple cell types including endothelial cells …

Simple Summary In this review, the thorny issue of glioblastoma models is addressed, with a
focus on 3D in vitro models. In the first part of the manuscript, glioblastoma features and …

Glioblastoma (GBM) is the most malignant brain tumor and one of the deadliest types of
solid cancer overall. Despite aggressive therapeutic approaches consisting of maximum …

Glioblastoma (GBM) is the most common and devastating primary brain tumor, leading to a
uniform fatality after diagnosis. A major difficulty in eradicating GBM is the presence of …