Chemotherapy is one of the primary treatments for malignant tumors. However, the acquired
drug resistance hinders clinical efficacy and leads to treatment failure in most patients …

Epigenetic factors are critical regulators of biological and pathological mechanisms and they
could interact with different molecular pathways. Targeting epigenetic factors has been an …

Simple Summary Extracellular vesicles (EVs) are cell-derived membrane-surrounded
vesicles that carry bioactive molecules and deliver them to recipient cells. Classical EVs are …

The macrophages are abundantly found in TME and their M2 polarization is in favor of tumor
malignancy. On the other hand, non-coding RNAs (ncRNAs) can modulate macrophage …

Exosome-mediated delivery of circular RNAs (circRNAs) is implicated in cancer progression.
However, the role of exosomal circRNAs in the chemotherapy resistance of tumours remains …

This review provides a comprehensive overview of our understanding of the role that
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …

Exosomes, the small extracellular vesicles, are released by multiple cell types, including
tumor cells, and represent a novel avenue for intercellular communication via transferring …

A major obstacle to chemotherapeutic success in cancer treatment is the development of
drug resistance. This occurs when a tumour fails to reduce in size after treatment or when …

Exosomes are extracellular vesicles with a diameter of 30–150 nm that function in mediating
intercellular communication and intercellular material exchange. The liposomal membrane …

Malignant melanoma is one of the most aggressive human neoplasms responsible for the
majority of skin cancer-related deaths in its advanced stages. Achieving a thorough …