The search for anticancer metal-based drugs alternative to platinum derivatives could not
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …

Copper is an endogenous metal ion that has been studied to prepare a new antitumoral
agent with less side-effects. Copper is involved as a cofactor in several enzymes, in ROS …

The interpretation of in vitro cytotoxicity data of Cu (II)-1, 10-phenanthroline (phen)
complexes normally does not take into account the speciation that complexes undergo in …

Platinum drugs continue to dominate medical oncology treatments but they have
shortcomings associated with their use including dose-limiting toxic side effects and …

Cancer is the abnormal division and multiplication of cells in an organ or tissue. It is the
second leading cause of death globally. There are various types of cancer such as prostate …

A novel Mn (II) complex with 1, 3-Thiazolidine-2, 4-dicarboxylic acid and 1, 10
phenanthroline has been synthesized, and its FT-IR, FT-Raman and UV–vis spectra have …

Zinc (II) complexes bearing N-salicylideneglycinate (Sal-Gly) and 1, 10-phenanthroline
(phen) or phenanthroline derivatives [NN= 5-chloro-1, 10-phenanthroline, 5-amine-1, 10 …

Five new copper (II) complexes of the type [Cu (Nsingle bondO)(Nsingle bondN)(ClO 4) 2],
in which Nsingle bondO= 4-fluorophenoxyacetic acid hydrazide (4-FH) or 4-nitrobenzoic …

The emergence of drug resistance is a major obstacle for the success of targeted therapy in
melanoma. Additionally, conventional chemotherapy has not been effective as drug …

1, 10-Phenanthroline (phen) is one of the most popular ligands ever used in coordination
chemistry due to its strong affinity for a wide range of metals with various oxidation states. Its …