Migraine is an extremely disabling, common neurological disorder characterized by a
complex neurobiology, involving a series of central and peripheral nervous system areas …

Migraine is a complex condition in which genetic predisposition interacts with other
biological and environmental factors determining its course. A hyperresponsive brain cortex …

Background In this study, we aimed to evaluate the efficacy, safety, and tolerability of
atogepant for the preventive treatment of chronic migraine. Methods We did this randomised …

Background Several novel treatments targeting the calcitonin gene-related peptide pathway
have been developed for migraine. We evaluated the efficacy of these medications …

Migraine and neuropathic pain (NP) are both painful, disabling, chronic conditions which
exhibit some symptom similarities and are thus considered to share a common etiology. The …

Tension-type headache (TTH) and migraine are two common primary headaches
distinguished by clinical characteristics according to the 3rd edition of the International …

The understanding of idiopathic intracranial hypertension (IIH) has evolved over the past few
years. Previously, IIH was considered a disease exclusively affecting the neuro-ophthalmic …

Background Clinical trials have shown that erenumab is effective and well-tolerated for the
preventive treatment of chronic migraine. To extend the results from clinical trials, we …

Background Pituitary adenylate cyclase-activating polypeptide (PACAP), structurally related
to vasoactive intestinal peptide (VIP), is one of the important mediators in the pathogenesis …

Introduction Migraine prophylactic therapy has changed over recent years with the
development and approval of monoclonal antibodies (mAbs) targeting the calcitonin gene …