[HTML][HTML] Colon cancer and colorectal cancer: Prevention and treatment by potential natural products

MR Islam, S Akash, MM Rahman, FT Nowrin… - Chemico-biological …, 2022 - Elsevier
Colon cancer affects both men and women and is the world's second most significant cause
of cancer-related mortality. Colon cancer death rates have risen worldwide due to the …

Rising incidence of early-onset colorectal cancer—A call to action

N Akimoto, T Ugai, R Zhong, T Hamada… - Nature reviews Clinical …, 2021 - nature.com
The incidence of early-onset colorectal cancer (CRC), which occurs in individuals< 50 years
of age, has been increasing worldwide and particularly in high-income countries. The …

Panitumumab vs bevacizumab added to standard first-line chemotherapy and overall survival among patients with RAS wild-type, left-sided metastatic colorectal …

J Watanabe, K Muro, K Shitara, K Yamazaki… - Jama, 2023 - jamanetwork.com
Importance For patients withRASwild-type metastatic colorectal cancer, adding anti–
epidermal growth factor receptor (anti-EGFR) or anti–vascular endothelial growth factor (anti …

Enterotypes in the landscape of gut microbial community composition

PI Costea, F Hildebrand, M Arumugam, F Bäckhed… - Nature …, 2018 - nature.com
Population stratification is a useful approach for a better understanding of complex
biological problems in human health and wellbeing. The proposal that such stratification …

[HTML][HTML] Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR …

D Arnold, B Lueza, JY Douillard, M Peeters, HJ Lenz… - Annals of oncology, 2017 - Elsevier
Background There is increasing evidence that metastatic colorectal cancer (mCRC) is a
genetically heterogeneous disease and that tumours arising from different sides of the colon …

[HTML][HTML] The relevance of primary tumour location in patients with metastatic colorectal cancer: a meta-analysis of first-line clinical trials

JW Holch, I Ricard, S Stintzing, DP Modest… - European Journal of …, 2017 - Elsevier
Background Retrospective subgroup analyses suggest that primary tumour location (PTL)
has a prognostic importance and relates to response to targeted therapy. Methods We …

Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis

K Mima, R Nishihara, ZR Qian, Y Cao, Y Sukawa… - Gut, 2016 - gut.bmj.com
Objective Accumulating evidence links the intestinal microbiota and colorectal
carcinogenesis. Fusobacterium nucleatum may promote colorectal tumour growth and …

Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells

U Testa, E Pelosi, G Castelli - Medical Sciences, 2018 - mdpi.com
Colon cancer is the third most common cancer worldwide. Most colorectal cancer
occurrences are sporadic, not related to genetic predisposition or family history; however, 20 …

Epigenetic alterations in colorectal cancer: emerging biomarkers

Y Okugawa, WM Grady, A Goel - Gastroenterology, 2015 - Elsevier
Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the
fundamental processes driving the initiation and progression of CRC is the accumulation of …

Nutrients, foods, and colorectal cancer prevention

M Song, WS Garrett, AT Chan - Gastroenterology, 2015 - Elsevier
Diet has an important role in the development of colorectal cancer. In the past few decades,
findings from extensive epidemiologic and experimental investigations have linked …