Multidrug resistance in Escherichia coli has become a worrying issue that is increasingly
observed in human but also in veterinary medicine worldwide. E. coli is intrinsically …

In 2008, a previously unknown Escherichia coli clonal group, sequence type 131 (ST131),
was identified on three continents. Today, ST131 is the predominant E. coli lineage among …

Background Antimicrobial resistance (AMR) poses a major threat to human health around
the world. Previous publications have estimated the effect of AMR on incidence, deaths …

Resistance to therapeutic antimicrobial agents is recognized as a growing problem for both
human and veterinary medicine, and the need to address the issue in both of these linked …

Background Extended-spectrum β-lactamase-producing Escherichia coli isolates (ESBL-E
coli) cause more than 5000 cases of bacteraemias annually in the UK. The contribution of …

Extended-spectrum cephalosporins (ESCs) are critically important antimicrobial agents for
human and veterinary medicine. ESC resistance (ESC-R) genes have spread worldwide …

To find out whether food-producing animals (FPAs) are a source of extraintestinal expanded-
spectrum cephalosporin-resistant Escherichia coli (ESCR-EC) infections in humans …

In recent years, extended-spectrum β-lactamases (ESBL) producing bacteria have been
found in livestock, mainly as asymptomatic colonizers. The zoonotic risk for people working …

This chapter focuses on acquired resistance mechanisms in bacterial pathogens of human
and animal origin, including examples of transfer of resistant pathogens between hosts and …

For several billion years, bacteria have developed mechanisms to resist antibacterial
substances. In modern time, antibiotics are frequently used in veterinary and human …