Dietary phenolic compounds: their health benefits and association with the gut microbiota
Y Matsumura, M Kitabatake, S Kayano, T Ito - Antioxidants, 2023 - mdpi.com
Oxidative stress causes various diseases, such as type II diabetes and dyslipidemia, while
antioxidants in foods may prevent a number of diseases and delay aging by exerting their …
antioxidants in foods may prevent a number of diseases and delay aging by exerting their …
[HTML][HTML] Harnessing role of sesamol and its nanoformulations against neurodegenerative diseases
Sesamol is a lignan of sesame seeds and a natural phenolic molecule that has emerged as
a useful medical agent. Sesamol is a non-toxic phytoconstituent, which exerts certain …
a useful medical agent. Sesamol is a non-toxic phytoconstituent, which exerts certain …
Therapeutic considerations of bioactive compounds in Alzheimer's disease and Parkinson's disease: Dissecting the molecular pathways
BC Phukan, R Roy, I Gahatraj… - Phytotherapy …, 2023 - Wiley Online Library
Leading neurodegenerative diseases Alzheimer's disease (AD) and Parkinson's disease
(PD) are characterized by the impairment of memory and motor functions, respectively …
(PD) are characterized by the impairment of memory and motor functions, respectively …
Sesamol Mitigates Chronic Iron Overload‐Induced Cognitive Impairment and Systemic Inflammation via IL‐6 and DMT1 Regulation
Y Wang, Y Zhang, X Wang, Q Li, Y Zhao… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope Excessive iron contributes to oxidative damage and cognitive decline in Alzheimer's
disease. Sesamol, a compound in sesame oil that exhibits both anti‐inflammatory and …
disease. Sesamol, a compound in sesame oil that exhibits both anti‐inflammatory and …
Torreya grandis oil attenuates cognitive impairment in scopolamine-induced mice
J Ma, T Yuan, Y Gao, X Zeng, Z Liu, J Gao - Food & Function, 2023 - pubs.rsc.org
The oil of Torreya grandis (TGO), a common nut in China, is considered to be a bioactive
edible oil and has a great value in functional food development. In this study, the …
edible oil and has a great value in functional food development. In this study, the …
Lignan-Rich Sesame (Sesamum indicum L.) Cultivar Exhibits In Vitro Anti-Cholinesterase Activity, Anti-Neurotoxicity in Amyloid-β Induced SH-SY5Y Cells, and …
MY Kim, S Kim, J Lee, JI Kim, E Oh, SW Kim, E Lee… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease, a major cause of dementia, is characterized by impaired cholinergic
function, increased oxidative stress, and amyloid cascade induction. Sesame lignans have …
function, increased oxidative stress, and amyloid cascade induction. Sesame lignans have …
Design, Synthesis, and Activity Evaluation of Fluorine-Containing Scopolamine Analogues as Potential Antidepressants
L Wang, X Zhu, B Wang, Y Wang, M Wang… - Journal of Medicinal …, 2024 - ACS Publications
This study aimed to develop novel rapid-acting antidepressants with sustained efficacy and
favorable safety profiles. We designed and synthesized a series of fluorine-containing …
favorable safety profiles. We designed and synthesized a series of fluorine-containing …
Sesamol: A lignan in sesame seeds with potent anti-inflammatory and immunomodulatory properties
AF Majdalawieh, SH Ahari, SM Yousef… - European Journal of …, 2023 - Elsevier
Inflammation is associated with the development and progression of a plethora of diseases
including joint, metabolic, neurological, hepatic, and renal disorders. Sesamol, derived from …
including joint, metabolic, neurological, hepatic, and renal disorders. Sesamol, derived from …
Effects of the ApoE genotype on cognitive function in aging mice fed with a high-fat diet and the protective potential of n-3 polyunsaturated fatty acids
X Zhang, T Xie, S Zhou, Y Yuan, W Chen, J Zheng… - Food & Function, 2024 - pubs.rsc.org
The ApoE4 allele is the strongest genetic determinant for Alzheimer's disease (AD), while
obesity is a strong environmental risk for AD. The modulatory effect of the ApoE genotype on …
obesity is a strong environmental risk for AD. The modulatory effect of the ApoE genotype on …
A novel neuroprotective peptide YVYAETY identified and screened from Flammulina velutipes protein hydrolysates attenuates scopolamine-induced cognitive …
Y Dong, Q Hu, L Zhao, G Ma, N Ma, J Zhang, Y Ji… - Food & Function, 2024 - pubs.rsc.org
Flammulina velutipes protein hydrolysates are known for their abundant amino acids and
excellent developmental values. This study aimed to identify and screen neuroprotective …
excellent developmental values. This study aimed to identify and screen neuroprotective …