Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry

SN Palacios-Rápalo, LA De Jesus-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …

Lipid raft involvement in signal transduction in cancer cell survival, cell death and metastasis

B Li, Y Qin, X Yu, X Xu, W Yu - Cell proliferation, 2022 - Wiley Online Library
Lipid rafts are cholesterol‐and sphingolipid‐enriched specialized membrane domains within
the plasma membrane. Lipid rafts regulate the density and activity of signal receptors by …

The lipid rafts in cancer stem cell: a target to eradicate cancer

S Zhang, N Zhu, HF Li, J Gu, CJ Zhang, DF Liao… - Stem Cell Research & …, 2022 - Springer
Cancer stem cells (CSCs) are a subpopulation of cancer cells with stem cell properties that
sustain cancers, which may be responsible for cancer metastasis or recurrence. Lipid rafts …

Effect of cholesterol on biomimetic membrane curvature and coronavirus fusion peptide encapsulation

I Milogrodzka, DT Nguyen Pham, GR Sama… - ACS …, 2023 - ACS Publications
Biomimetic cubic phases can be used for protein encapsulation in a variety of applications
such as biosensors and drug delivery. Cubic phases with a high concentration of cholesterol …

Diversity of lipid function in atherogenesis: a focus on endothelial mechanobiology

S Kotlyarov - International journal of molecular sciences, 2021 - mdpi.com
Atherosclerosis is one of the most important problems in modern medicine. Its high
prevalence and social significance determine the need for a better understanding of the …

Murine endothelial serine palmitoyltransferase 1 (SPTLC1) is required for vascular development and systemic sphingolipid homeostasis

A Kuo, A Checa, C Niaudet, B Jung, Z Fu… - Elife, 2022 - elifesciences.org
Serine palmitoyl transferase (SPT), the rate-limiting enzyme in the de novo synthesis of
sphingolipids (SL), is needed for embryonic development, physiological homeostasis, and …

[HTML][HTML] Zebrafish mutants provide insights into Apolipoprotein B functions during embryonic development and pathological conditions

H Templehof, N Moshe, I Avraham-Davidi, K Yaniv - JCI insight, 2021 - ncbi.nlm.nih.gov
Apolipoprotein B (ApoB) is the primary protein of chylomicrons, VLDLs, and LDLs and is
essential for their production. Defects in ApoB synthesis and secretion result in several …

Research advances on the role of lipids in the life cycle of human coronaviruses

C Ding, Y Chen, G Miao, Z Qi - Microorganisms, 2023 - mdpi.com
Coronaviruses (CoVs) are emerging pathogens with a significant potential to cause life-
threatening harm to human health. Since the beginning of the 21st century, three highly …

AQP3-dependent PI3K/Akt modulation in breast cancer cells

M Mlinarić, I Lučić, L Milković, IV da Silva… - International journal of …, 2023 - mdpi.com
Aquaporin 3 (AQP3) is a peroxiporin, a membrane protein that channels hydrogen peroxide
in addition to water and glycerol. AQP3 expression also correlates with tumor progression …

[HTML][HTML] Shedding light on membrane rafts structure and dynamics in living cells

JA Nieto-Garai, M Lorizate, FX Contreras - Biochimica et Biophysica Acta …, 2022 - Elsevier
Cellular membranes are fundamental building blocks regulating an extensive repertoire of
biological functions. These structures contain lipids and membrane proteins that are known …