We compared the cell cycle regulation of thymidine kinase (TK) after centrifugal elutriation in
normal human and mouse cells (primary cells, diploid fibroblasts) with its expression in cells …

Here we report the expression of major pyrimidine metabolising enzymes in pancreatic
cancer cell lines, chronic pancreatitis tissue and human pancreatic cancer and the in vitro …

The expression of thymidine kinase—an enzyme of the DNA precursor pathway—is strictly
regulated during the normal cellular cycle, but is much higher and permanently expressed in …

Deoxycytidine kinase enzyme activity and deoxycitidine kinase mRNA content were
determined at different positions of the cell cycle in permanent cell lines. There was no …

We determined the cell cycle-dependent fluctuation of mRNAs that encode different
enzymes of the deoxynucleotide metabolism in permanent cell lines of human and murine …

Fetal cells occur in maternal blood in a substantial proportion of normal pregnancies.
Several different approaches have been used to detect and enrich these cells for non …

Abstract The compounds WHI-05 (5-bromo-6-methoxy-5, 6-dihydro-3′-azidothymidine-5′-
[p-methoxyphenyl] methoxyalaninyl phosphate) and WHI-07 (5-bromo-6-methoxy-5, 6 …

A cytofluorometric assay allowing the measurement of thymidine phosphorylation in single
cells had been established (Hengstschläger & Wawra, 1993). This assay enables us to …

Using a cytofluorometric assay, we studied the time course of thymidine kinase activity
during the cell-cycle in logarithmically growing cells. Two different patterns were found …