Background Amyotrophic lateral sclerosis is a fatal neurodegenerative disease with few
therapeutic options. Mild obesity is associated with greater survival in patients with the …

Complementary and Alternative Therapies in Amyotrophic Lateral Sclerosis - Neurologic Clinics
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Studies have suggested that obesity is associated with better prognosis among individuals
with various types of neurodegenerative diseases, and while some studies suggest that the …

Background: Patients with amyotrophic lateral sclerosis (ALS) experience progressive limb
weakness, muscle atrophy, and dysphagia, making them vulnerable to insufficient energy …

Abstract Rationale Hypermetabolism (HM) in Amyotrophic lateral sclerosis (ALS) is the
reflection of a high energy metabolic level, but this alteration seems controversial. The main …

Background Motor neuron degeneration and malnutrition alter body composition in
amyotrophic lateral sclerosis (ALS). Resulting losses of weight, fat mass (FM), and fat-free …

This study was undertaken to determine which symptoms are perceived to be most
problematic for patients with ALS and how their severity changes over time. A retrospective …

Background: There has been no comprehensive longitudinal study of pulmonary functions
(PFTS) in ALS determining which measure is most sensitive to declines in respiratory …

Background: Although noninvasive ventilation (NIV) improves survival and quality of life
(QOL) in ALS, use of NIV is suboptimal. Objective: To determine compliance with “early” NIV …

Amyotrophic lateral sclerosis (ALS) arises from neuronal death due to complex interactions
of genetic, molecular, and environmental factors. Currently, only two drugs, riluzole and …