How introns enhance gene expression

O Shaul - The international journal of biochemistry & cell biology, 2017 - Elsevier
In many eukaryotes, including mammals, plants, yeast, and insects, introns can increase
gene expression without functioning as a binding site for transcription factors. This …

Intron-mediated regulation of gene expression

AB Rose - Nuclear pre-mRNA processing in plants, 2008 - Springer
Introns can significantly affect gene expression in plants and many other eukaryotes in a
variety of ways. Several types of gene regulation, both positive and negative, that involve …

Efficient promoter cassettes for enhanced expression of foreign genes in dicotyledonous and monocotyledonous plants

I Mitsuhara, M Ugaki, H Hirochika… - Plant and Cell …, 1996 - academic.oup.com
A series of chimeric promoters for higher-level expression of foreign genes in plants was
constructed as fusions of a gene for rβ-glucuronidase (GUS) with the terminator of a gene for …

Enhanced ADP-glucose pyrophosphorylase activity in wheat endosperm increases seed yield

ED Smidansky, M Clancy, FD Meyer… - Proceedings of the …, 2002 - National Acad Sciences
Yield in cereals is a function of seed number and weight; both parameters are largely
controlled by seed sink strength. The allosteric enzyme ADP-glucose pyrophosphorylase …

Dissection of maize kernel composition and starch production by candidate gene association

LM Wilson, SR Whitt, AM Ibaéñez, TR Rocheford… - The Plant …, 2004 - academic.oup.com
Cereal starch production forms the basis of subsistence for much of the world's human and
domesticated animal populations. Starch concentration and composition in the maize (Zea …

The enduring mystery of intron-mediated enhancement

JE Gallegos, AB Rose - Plant Science, 2015 - Elsevier
Within two years of their discovery in 1977, introns were found to have a positive effect on
gene expression. Numerous examples of stimulatory introns have been described since …

The barley Hooded mutation caused by a duplication in a homeobox gene intron

KJ Müller, N Romano, O Gerstner, F Garcia-Marotot… - Nature, 1995 - nature.com
IN barley (Hordeum vulgare L.) the unit of inflorescence is the spikelet, which bears a fertile
bract, the lemma, and the floret consisting of palea, two lodicules, three stamens and the …

Seed yield and plant biomass increases in rice are conferred by deregulation of endosperm ADP-glucose pyrophosphorylase

ED Smidansky, JM Martin, CL Hannah, AM Fischer… - Planta, 2003 - Springer
In this work we test the hypothesis that yield of rice (Oryza sativa L.) can be enhanced by
increasing endosperm activity of ADP-glucose pyrophosphorylase (AGP), a key enzyme in …

Comparative and functional analysis of intron-mediated enhancement signals reveals conserved features among plants

G Parra, K Bradnam, AB Rose, I Korf - Nucleic acids research, 2011 - academic.oup.com
Introns in a wide range of organisms including plants, animals and fungi are able to increase
the expression of the gene that they are contained in. This process of intron-mediated …

Promoter-Proximal Introns in Arabidopsis thaliana Are Enriched in Dispersed Signals that Elevate Gene Expression

AB Rose, T Elfersi, G Parra, I Korf - The Plant Cell, 2008 - academic.oup.com
Introns that elevate mRNA accumulation have been found in a wide range of eukaryotes.
However, not all introns affect gene expression, and direct testing is currently the only way to …