Sickle cell disease is the most common cause of stroke in childhood, both ischaemic and
haemorrhagic, and it also affects adults with the condition. Without any screening or …

Pediatric patients with sickle cell disease (SCD) experience a range of medical
complications that result in significant morbidity and mortality. Recent advances in …

Children with sickle cell disease (SCD) demonstrate cerebral hemodynamic stress and are
at high risk of strokes. We hypothesized that curative hematopoietic stem cell transplant …

Research in sickle cell anemia (SCA) has used, with limited race-matched control data,
binary categorization of patients according to the presence or absence of silent cerebral …

Previous studies have pointed to a role for regional cerebral hemodynamic stress in
neurological complications in patients with sickle cell anemia (SCA), with watershed regions …

Prior studies have described high venous signal qualitatively using arterial spin labelling
(ASL) in patients with sickle cell anemia (SCA), consistent with arteriovenous shunting. We …

Sickle cell disease (SCD) is an inherited hemoglobinopathy with an increased risk of
neurological complications. Due to anemia and other factors related to the underlying …

Gliomas are a common and aggressive kind of brain tumour that is difficult to diagnose due
to their infiltrative development, variable clinical presentation, and complex behaviour …

Occlusion of cerebral blood vessels causes acute cerebral hypoxia—an important trigger of
ischemic white matter injury and stroke in sickle cell disease (SCD). While chronic hypoxia …

Sickle cell disease (SCD) is a genetic blood disorder that affects hemoglobin and increases
stroke risk, particularly in childhood. This review examines the pathophysiological …